With the aim of gathering temporal trends on bacterial epidemiology and resistance from multiple laboratories in China, the CHINET surveillance system was organized in 2005. Antimicrobial ...susceptibility testing was carried out according to a unified protocol using the Kirby-Bauer method or automated systems. Results were analyzed according to Clinical and Laboratory Standards Institute (CLSI) 2014 definitions. Between 2005 and 2014, the number of bacterial isolates ranged between 22 774 and 84 572 annually. Rates of extended-spectrum β-lactamase production among Escherichia coli isolates were stable, between 51.7 and 55.8%. Resistance of E. coli and Klebsiella pneumoniae to amikacin, ciprofloxacin, piperacillin/tazobactam and cefoperazone/sulbactam decreased with time. Carbapenem resistance among K. pneumoniae isolates increased from 2.4 to 13.4%. Resistance of Pseudomonas aeruginosa strains against all of antimicrobial agents tested including imipenem and meropenem decreased with time. On the contrary, resistance of Acinetobacter baumannii strains to carbapenems increased from 31 to 66.7%. A marked decrease of methicillin resistance from 69% in 2005 to 44.6% in 2014 was observed for Staphylococcus aureus. Carbapenem resistance rates in K. pneumoniae and A. baumannii in China are high. Our results indicate the importance of bacterial surveillance studies.
Abstract
Van der Waals magnets have emerged as a fertile ground for the exploration of highly tunable spin physics and spin-related technology. Two-dimensional (2D) magnons in van der Waals magnets ...are collective excitation of spins under strong confinement. Although considerable progress has been made in understanding 2D magnons, a crucial magnon device called the van der Waals magnon valve, in which the magnon signal can be completely and repeatedly turned on and off electrically, has yet to be realized. Here we demonstrate such magnon valves based on van der Waals antiferromagnetic insulator MnPS
3
. By applying DC electric current through the gate electrode, we show that the second harmonic thermal magnon (SHM) signal can be tuned from positive to negative. The guaranteed zero crossing during this tuning demonstrates a complete blocking of SHM transmission, arising from the nonlinear gate dependence of the non-equilibrium magnon density in the 2D spin channel. Using the switchable magnon valves we demonstrate a magnon-based inverter. These results illustrate the potential of van der Waals anti-ferromagnets for studying highly tunable spin-wave physics and for application in magnon-base circuitry in future information technology.
Aims. We derive the morphology of the stellar component in the outer halo volume, and search for possible overdensities due to substructures therein. Methods. We made use of some of the data releases ...of the spectroscopic survey LAMOST DR8-DR9 in tandem with distance determinations for two subsamples, that is, of K-giants and M-giants, respectively, making up 60 000 stars. These distance are obtained through Bayesian techniques that derive absolute magnitudes as a function of measured spectroscopic parameters. Our calculation of the density from these catalogues requires: (1) derivation of the selection function; and (2) a correction for the convolution of the distance errors, which we carried out with Lucy’s inversion of the corresponding integral equation. Results. The stellar density distribution of the outer halo (distance to the Galactic centre, r G , of between 25 and 90 kpc) is a smooth monotonously decreasing function with a dependence of approximately ρ ∝ r G −n , with n = 4.6 ± 0.4 for K-giants and n = 4.5 ± 0.2 for M-giants, and with a insignificant oblateness. The value of n is independent of the angular distance to the Sagittarius tidal stream plane, which is what would be expected if such a stream did not exist in the anticenter positions or had a negligible imprint in the density distribution in the outer halo. Apart from random fluctuations or minor anomalies in some lines of sight, we do not see substructures superimposed in the outer halo volume within the resolution that we are using and limited by the error bars. This constrains the mass of over- and under-densities in the outer halo to be of ≲10 3 M ⊙ deg −2 , whereas the total mass of the stellar halo, including inner and outer parts, is ∼7 × 10 8 M ⊙ .
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