A Black Hole Nova Obscured by an Inner Disk Torus Corral-Santana, J. M.; Casares, J.; Muñoz-Darias, T. ...
Science (American Association for the Advancement of Science),
03/2013, Letnik:
339, Številka:
6123
Journal Article
Recenzirano
Odprti dostop
Stellar-mass black holes (BHs) are mostly found in x-ray transients, a subclass of x-ray binaries that exhibit violent outbursts. None of the 50 galactic BHs known show eclipses, which is surprising ...for a random distribution of inclinations. Swift J1357.2—093313 is a very faint x-ray transient detected in 2011. On the basis of spectroscopic evidence, we show that it contains a BH in a 2.8-hour orbital period. Further, high—time-resolution optical light curves display profound dips without x-ray counterparts. The observed properties are best explained by the presence of an obscuring toroidal structure moving outward in the inner disk, seen at very high inclination. This observational feature should play a key role in models of inner accretion flows and jet collimation mechanisms in stellar-mass BHs.
Mining is an essential human activity, but results in several environmental impacts, notably the contamination of ground and surface water through the presence of toxic substances such as metals and ...sulfates in mine drainage. Permeable reactive barriers (PRB) have been applied to remediate this environmental impact, but the high costs associated with the maintenance of this system are still a challenge. The main objective of this study was to evaluate the use of kraft pulp mill alkaline residues, known as dregs and grits, as material for PRB, and to determine their capacity for retaining copper and sulfate. The work was carried out in laboratory adsorption kinetics assays, batch assays and column tests. Tests for elemental characterization, point of zero charge, acid neutralization capacity, total porosity, bulk density and moisture of the dregs and grits were conducted. The results showed high retention of Cu due to a chemical precipitation mechanism, notably for dregs (99%) at 5 min in adsorption kinetics. The grits presented similar results after 180 min for the same assay. Sulfate retention was effective at pH below 5, with an efficiency of 79% and 89% for dregs and grits, respectively. Dregs presented the best results for acid drainage remediation, notably with a solid:liquid (S:L) ratio of 1:10.
We model the fluids involved in the alteration processes recorded in the Sheep bed Member mudstones of Yellowknife Bay (YKB), Gale crater, Mars, as revealed by the Mars Science Laboratory Curiosity ...rover investigations. We compare the Gale crater waters with fluids modeled for shergottites, nakhlites, and the ancient meteorite ALH 84001, as well as rocks analyzed by the Mars Exploration rovers, and with terrestrial ground and surface waters. The aqueous solution present during sediment alteration associated with phyllosilicate formation at Gale was high in Na, K, and Si; had low Mg, Fe, and Al concentrations relative to terrestrial ground waters such as the Deccan Traps and other modeled Mars fluids; and had near neutral to alkaline pH. Ca and S species were present in the 10(exp -3) to 10(exp -2) concentration range. A fluid local to Gale crater strata produced the alteration products observed by Curiosity and subsequent evaporation of this ground water- type fluid formed impure sulfate- and silica-rich deposits veins or horizons. In a second, separate stage of alteration, partial dissolution of this sulfate-rich layer in Yellowknife Bay,or beyond, led to the pure sulfate veins observed in YKB. This scenario is analogous to similar processes identified at a terrestrial site in Triassic sediments with gypsum veins of the Mercia Mudstone Group in Watchet Bay, UK.
: Galacto‐oligosaccharides (GOS) have now been definitely established as prebiotic ingredients after in vitro and animal and human in vivo studies. Currently, GOS are produced by glycoside ...hydrolases (GH) using lactose as substrate. Converting lactose into GOS by GH results in mixtures containing GOS of different degrees of polymerization (DP), unreacted lactose, and monomeric sugars (glucose and galactose). Recent and future developments in the production of GOS aim at delivering purer and more efficient mixtures. To produce high‐GOS‐content mixtures, GH should not only have good ability to catalyze the transgalactosylation reaction relative to hydrolysis, but also have low affinity for the GOS formed relative to the affinity for lactose. In this article, several microbial GH, proposed for the synthesis of GOS, are hierarchized according to the referred performance indicators. In addition, strategies for process improvement are discussed. Besides the differences in purity of GOS mixtures, differences in the position of the glycosidic linkages occur, because different enzymes have different regiochemical selectivity. Depending on oligosaccharide composition, GOS products will vary in terms of prebiotic activity, as well as other physiological effects. This review focuses on GOS production from synthesis to purification processes. Physicochemical characteristics, physiological effects, and applications of these prebiotic ingredients are summarized. Regulatory aspects of GOS‐containing food products are also highlighted with emphasis on the current process of health claims evaluation in Europe.
BACKGROUNDSpain has been one of the countries most affected by the COVID-19 pandemic. OBJECTIVETo create a registry of patients with COVID-19 hospitalized in Spain, in order to improve our knowledge ...of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. METHODSA multicentre retrospective cohort study, including consecutive patients hospitalized with confirmed COVID-19 throughout Spain. Epidemiological and clinical data, additional tests at admission and at seven days, treatments administered, and progress at 30 days of hospitalization were collected from electronic medical records. RESULTSUp to June 30th 2020, 15,111 patients from 150 hospitals were included. Their median age was 69.4 years (range: 18-102 years) and 57.2% were male. Prevalences of hypertension, dyslipidemia, and diabetes mellitus were 50.9%, 39.7%, and 19.4%, respectively. The most frequent symptoms were fever (84.2%) and cough (73.5%). High values of ferritin (73.5%), lactate dehydrogenase (73.9%), and D-dimer (63.8%), as well as lymphopenia (52.8%), were frequent. The most used antiviral drugs were hydroxychloroquine (85.6%) and lopinavir/ritonavir (61.4%); 33.1% developed respiratory distress. Overall mortality rate was 21.0%, with a marked increase with age (50-59 years: 4.7%, 60-69 years: 10.5%, 70-79 years: 26.9%, ≥80 years: 46.0%). CONCLUSIONSThe SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality.
We present H-band spectra of the candidate counterparts of five ultraluminous X-ray sources (ULXs; two in NGC 925, two in NGC 4136 and Holmberg II X-1) obtained with Keck/MOSFIRE (Multi-Object ...Spectrometer for Infra-Red Exploration). The candidate counterparts of two ULXs (J022721+333500 in NGC 925 and J120922+295559 in NGC 4136) have spectra consistent with (M-type) red supergiants (RSGs). We obtained two epochs of spectroscopy of the candidate counterpart to J022721+333500, separated by 10 months, but discovered no radial velocity variations with a 2σ upper limit of 40 km s−1. If the RSG is the donor star of the ULX, the most likely options are that either the system is seen at low inclination (<40°) or the black hole mass is less than 100 M⊙, unless the orbital period is longer than 6 years, in which case the obtained limit is not constraining. The spectrum of the counterpart to J120922+295559 shows emission lines on top of its stellar spectrum, and the remaining three counterparts do not show absorption lines that can be associated with the atmosphere of a star; their spectra are instead dominated by emission lines. Those counterparts with RSG spectra may be used in the future to search for radial velocity variations, and, if those are present, determine dynamical constraints on the mass of the accretor.
Patients with refractory severe aplastic anemia (SAA) who lack a matched sibling or unrelated donor need new therapeutic approaches. Hematopoietic SCT (HSCT) using mismatched or haploidentical ...related donors has been used in the past, but was associated with a significant risk of GVHD and mortality. Recently, the use of post-transplant cyclophosphamide (Cy) has been shown to be an effective strategy to prevent GVHD in recipients of haploidentical HSCT, but the majority of reports have focused on patients with hematology malignancies. We describe the outcome of 16 patients who underwent haploidentical transplantation using a reduced-intensity conditioning regimen with post-transplant Cy. Stem cell sources were BM (N=13) or PBSCs (N=3). The rate of neutrophil engraftment was 94% and of platelet engraftment was 75%. Two patients had secondary graft failure and were successfully salvaged with another transplant. Three patients developed acute GVHD being grades 2-4 in two. Five patients have died and the 1-year OS was 67.1% (95% confidence interval: 36.5-86.4%). In our small series, the use of a reduced-intensity conditioning with post-transplant Cy in haploidentical BMT was associated with high rates of engraftment and low risk of GVHD in patients with relapsed/refractory SAA.
Abstract
Fast X-ray Transients (FXTs) are X-ray flares with durations ranging from a few hundred seconds to a few hours. Possible origins include the tidal disruption of a white dwarf by an ...intermediate-mass black hole, a supernova shock breakout, or a binary neutron star merger. We present the X-ray light curve and spectrum as well as deep optical imaging of the FXT XRT 210423, which has been suggested to be powered by a magnetar produced in a binary neutron star merger. Our Very Large Telescope and Gran Telescopio Canarias (GTC) observations began on 2021 May 6, thirteen days after the onset of the flare. No transient optical counterpart is found in the 1.″ (3
σ
) X-ray uncertainty region of the source to a depth
g
s
= 27.0 AB mag. (We use the word “counterpart” for any transient light in a wave band other than the original X-ray detection wave band, whereas the word “host” refers to the host galaxy.) A candidate host lies within the 1.″ X-ray uncertainty region with a magnitude of 25.9 ± 0.1 in the GTC/HiPERCAM
g
s
filter. Due to its faintness, it was not detected in other bands, precluding a photometric redshift determination. We detect two additional candidate host galaxies: one with
z
spec
= 1.5082 ± 0.0001 and an offset of 4.″2 ± 1.″ (37 ± 9 kpc) from the FXT, and another one with
z
phot
=
1.04
−
0.14
+
0.22
and an offset of 3.″6 ± 1.″ (30 ± 8 kpc). Based on the properties of all the prospective hosts, we favor a binary neutron star merger, as previously suggested in the literature, as the explanation for XRT 210423.
Objective
Animal models have suggested that anogenital distance (AGD) at birth reflects androgen levels during in utero development and predicts adult AGD. A recent study showed an association ...between perineal length and androgen levels in men, suggesting that serum testosterone levels in adulthood will depend on factors involved during the fetal period. The aim of this study is to assess the relationship between AGD measures and reproductive hormone levels in women.
Design
Cross‐sectional study conducted between February and November 2011.
Setting
University‐affiliated fertility clinics.
Population
100 young college students.
Methods
Physical and gynaecological examinations were conducted on university students. All participants provided a blood sample for determination of reproductive hormones and completed an epidemiological questionnaire on lifestyles and gynaecological history. We used multiple linear regression analysis to examine the associations between perineal length measurements anus‐fourchette (AGDAF) and anus‐clitoris (AGDAC) and reproductive hormone levels.
Main outcome measures
Anogenital distance measurements and reproductive hormone levels.
Results
In the multiple linear regression analyses, AGDAF was positively associated with serum testosterone levels. Serum testosterone increased 0.06 ng/ml (95%CI 0.01, 0.10; P = 0.02) for each 1‐cm increase in AGDAF. None of the measurements was associated with other reproductive hormones.
Conclusions
Anogenital distance may predict normal reproductive development in women, and may be a new tool of potential clinical interest to evaluate ovarian function. Our results suggest that serum testosterone levels in adulthood may depend on factors operating in the prenatal period.
Biomats that flourished in a fumarole located on the geothermal site
Los Azufres
(Mexico) were used as inocula to select aerobic and sulfate-reducing bacteria consortia for studying their capacity to ...reduce hexavalent chromium Cr(VI), aiming to use these consortia in biotransformation technologies. The sample site is characterized by slightly warm (nearly 27
∘
C), acid (pH 3) and about hypoxic (1.8 mg L
-
1
of dissolved oxygen) conditions. Four culture systems (2 aerobic and 2 anaerobic) were investigated, including their enzymatic activity, capacity to produce biofilms, and an analysis of the total bacterial populations. For the anaerobic condition (using sulfate and sulfur as electron acceptors), four pH values (from 2 to 8) and four carbon sources (pyruvate, glycerol, Na-lactate and Na-acetate) were probed. Significant biological Cr(VI) removal was observed for all the pH values probed, particularly during the first 12 h, being more effective at the most acid conditions. At a pH value of 4 and using pyruvate as carbon source, 100 mg L
-
1
of Cr(VI) were completely depleted in less than 12 h, while the use of Na-lactate was less effective but still reasonable. These results indicate that sulfate-reducing bacteria consortia from geothermal sites like the one studied here are capable of biotransforming Cr(VI) and have the potential to provide metal bioremediation technologies.
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