Highlights • Acute GvHD was protective of relapse after UCBT for children with ALL in first or second remission. • TBI-containing regimens improved outcomes after UCBT for pediatric ALL. • Risk of ...relapse after UCBT in second remission was lower using mismatched grafts.
Highlights • UCBT can provide durable engraftment in pediatric HLH patients. • UCBT may lead to long-term disease free survival in pediatric HLH patients. • Reduced toxicity conditioning is feasible ...with UCBT in pediatric HLH patients. • UCBT deserves further study in pediatric HLH patients in a larger prospective trial.
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