The histochemical detection of human papillomavirus (HPV) was performed using the tequnique of in situ hybridization from the formalin fixed paraffin embedded specimens of penile carcinoma and ...condyroma aquminatum. One of 19 penile cancer cases (5.3%) revealed the positive staining on the nuclei of the tumors for HPV type 16/18. However, the positive nuclei were scattered and localized in small part of the tumor which showed no koilocytosis. On the contrary, 11 of 12 condyloma aquminata cases (91.7%) showed positive staining on the nuclei of the tumors for HPV type 6/11, also 5 of the 11 cases (45.5%) revealed cross reaction for other type of HPV. The HPV types 6/11, 16/18 and 31/33/35 may be unrelated to the pathogenesis of the Japanese penile carcinoma. However, further study is necessary to evaluate that the number of HPV-DNA copy in our cases is too small, or the other type of HPV is responsibility.
A strong earthquake occurred in the southwest area of Hokkaido on July 12, in 1993. Immediately after the earthquake, Okushiri Island, which is near the seismic center, was seriously damaged by a ...seismic sea wave and a large fire. Edentulous and partially edentulous patients who lost their dentures during the emergency evacuation were treated. Information through questionnaires about dental problems were obtained at the time of the disaster. The results were as follows: 1. Eating was the most serious problem for persons who lost their dentures. 2. The menu and cooking methods of emergency relief foods were not considered suitable for persons who wore dentures and/or lost their dentures. 3. The results of questionnaires proved that the general public has little knowledge about dentures and/or denture wearers. 4. At the time of a disaster dentists must join as a member of the medical relief team to relieve dental problems or to secure masticatory function when long-term evacuation is predicted. 5. By 3-month follow-up, the dentures constructed and inserted by our team were found to be functioning satisfactorally and our prosthodontic approach was confirmed to be useful.