Background
Previous studies suggest that physical activity (PA) may afford protection against cancer risk.
Methods
This study evaluated longitudinal associations between PA and cancer mortality in ...the nationally representative Third National Health and Nutrition Examination Survey (NHANES III; 1988–1994), with an average follow‐up of 8.5y to mortality. Mortality was ascertained using National Death Index certificates. Metabolic equivalents (METS) were calculated from self‐reported PA collected in an in person‐interview. Cox‐proportional hazards models were used to compute hazard ratios (HR) for cancer mortality using SUDAAN in relation with level of PA.
Results
Any mention of PA vs. sedentary lifestyle was protective against cancer mortality (adjusted for age, race, sex, smoking, and BMI)(HR: 0.63, 95% CI: 0.47–0.84). High intensity PA was associated with further risk reduction (HR: 0.46, 95% CI: 0.27 – 0.78). Subjects in the highest vs. lowest tertile of METS had a 43% reduced risk of cancer mortality (HR:0.57, 95%CI: 0.41–0.80), p‐trend = 0.004. Leisure activity (gardening, dancing, yard work, and “other” active hobbies) was also associated with reduced risk of cancer mortality (HR:0.51, 95% CI:0.33–0.78).
Conclusion
In these preliminary analyses, all forms of PA confer protection against cancer mortality. PA should be considered as an integral part of cancer management.
Carotenoids, particularly lycopene, are thought to decrease prostate cancer risk, but the relationship between plasma carotenoid concentrations and risk in various populations has not been well ...characterized. Comparing 118 non-Hispanic Caucasian men mainly from southeast Texas with nonmetastatic prostate cancer with 52 healthy men from the same area, we conducted a case-control analysis evaluating associations between risk and plasma levels of total carotenoids, beta-cryptoxanthin, alpha- and trans-beta-carotene, lutein and zeaxanthin, total lycopenes, trans-lycopene, total cis-lycopenes, and cis-lycopene isoforms 1, 2, 3, and 5. Risk for men with high plasma levels of alpha-carotene, trans-beta-carotene, beta-cryptoxanthin, and lutein and zeaxanthin was less than half that for those with lower levels. In contrast, we observed no significant associations for total lycopenes, all-trans-lycopene, and cis-lycopene isomer peaks 2, 3, and 5, although high levels of cis-lycopene isomer peak 1 were inversely associated with risk. Analysis of men with aggressive disease (Gleason scores of greater than or equal to 7, n= 88) vs. less aggressive cases (Gleason scores of <7, n = 30) failed to reveal significant associations between carotenoid levels and the risk of diagnosis with aggressive disease. These findings suggest that, in these men, higher circulating levels of beta-cryptoxanthin, alpha-carotene, trans-beta-carotene, and lutein and zeaxanthin may contribute to lower prostate cancer risk but not to disease progression.
Trends in dietary fat and high-fat food intakes from 1991 to 2008 in the Framingham Heart Study participants Vadiveloo, Maya; Marc ScottauthorDepartment of Humanities and Social Sciences, New York University, 246 Greene Street, 3rd floor, New York, NY, 10003, USA; Paula QuatromoniauthorDepartment of Health Sciences, College of Health and Rehabilitation Sciences: Sargent College, Boston University, 635 Commonwealth Avenue, Boston, MA, 02215, USA ...
2015
Journal Article
Development and evaluation of the US Healthy Food Diversity index Vadiveloo, Maya; L. Beth DixonauthorDepartment of Public Health, Food Studies and Nutrition, David B. Falk College of Sport and Human Dynamics Syracuse University, 426 Ostrom Avenue, Syracuse, NY, 13244, USA; Tod MijanovichauthorDepartment of Humanities and Social Sciences in the Professions, Steinhardt School of Culture, Education, and Human Development, New York University, 411 Lafayette Street, 5th Floor, New York, NY, 10003, USA ...
2015
Journal Article