Aktuelle Geschehnisse wie das Inkrafttreten des Kodex "Leitlinien zur Sicherung guter wissenschaftlicher Praxis" der Deutschen Forschungsgemeinschaft (DFG) oder der Aufbau der Nationalen ...Forschungsdateninfrastruktur (NFDI) und der European Open Science Cloud (EOSC) stellen Anbietende, Produzierende und Nutzende von Forschungsdaten vor fachwissenschaftliche, technische, rechtliche und organisatorische Herausforderungen. Das Praxishandbuch Forschungsdatenmanagement behandelt umfassend alle relevanten Aspekte des Forschungsdatenmanagements und der derzeitigen Rahmenbedingungen im Datenökosystem. Insbesondere die praktischen Implikationen der Datenpolitik und des -rechts, des jeweiligen Datenmarkts, der Datenkultur, der persönlichen Qualifizierung, des Datenmanagements sowie des "FAIR"en Datentransfers und der Datennachnutzung werden untersucht. Das Praxishandbuch gibt überdies einen Überblick über Projekte, Entwicklungen und Herausforderungen beim Forschungsdatenmanagement.
The creation of the German National Research Data Infrastructure and the European Open Science Cloud is presenting the providers and users of research data with technical, legal, and organizational ...challenges. This thematically structured practical handbook looks at these challenges and provides researchers and CIOs as well as employees in institutions like libraries and computing centers with the necessary knowledge of research data management.
IntroductionSince the beginning of the pandemic in 2020, COVID-19 has changed the medical landscape. International recommendations for localized prostate cancer (PCa) include deferred treatment and ...adjusted therapeutic routines.Materials and methodsTo longitudinally evaluate changes in PCa treatment strategies in urological and radiotherapy departments in Germany, a link to a survey was sent to 134 institutions covering two representative baseline weeks prior to the pandemic and 13 weeks from March 2020 to February 2021. The questionnaire captured the numbers of radical prostatectomies, prostate biopsies and case numbers for conventional and hypofractionation radiotherapy. The results were evaluated using descriptive analyses.ResultsA total of 35% of the questionnaires were completed. PCa therapy increased by 6% in 2020 compared to 2019. At baseline, a total of 69 radiotherapy series and 164 radical prostatectomies (RPs) were documented. The decrease to 60% during the first wave of COVID-19 particularly affected low-risk PCa. The recovery throughout the summer months was followed by a renewed reduction to 58% at the end of 2020. After a gradual decline to 61% until July 2020, the number of prostate biopsies remained stable (89% to 98%) during the second wave. The use of RP fluctuated after an initial decrease without apparent prioritization of risk groups. Conventional fractionation was used in 66% of patients, followed by moderate hypofractionation (30%) and ultrahypofractionation (4%). One limitation was a potential selection bias of the selected weeks and the low response rate.ConclusionWhile the diagnosis and therapy of PCa were affected in both waves of the pandemic, the interim increase between the peaks led to a higher total number of patients in 2020 than in 2019. Recommendations regarding prioritization and fractionation routines were implemented heterogeneously, leaving unexplored potential for future pandemic challenges.
Topology of chalcogen chains Kłosiński, Adam; Brzezicki, Wojciech; Lau, Alexander ...
arXiv (Cornell University),
03/2023
Paper, Journal Article
Odprti dostop
We investigate the topological properties of the helical atomic chains occurring in elemental selenium and tellurium. We postulate a realistic model that includes spin-orbit interaction and show this ...to be topologically non-trivial, with a topological invariant protected by a crystalline symmetry. We describe the end-states, which are orbitally polarized, with an orbital density modulation strongly peaked at the edge. Furthermore, we propose a simplified model that decomposes into three orbital chains, allowing us to define a topological invariant protected by a crystalline symmetry. We contrast this result with recent observations made for the orbital Su-Schrieffer-Heeger model containing a \(p\)-orbital zigzag chain.
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