In previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance and other metabolism related disorders such as diabetes. ...Quercetin is a polyphenol, which is a derivative of plants, and has been shown in vitro as well as in a few animal models to have several potential anti-inflammatory as well as anticarcinogenic applications. The substance has also been shown to aid in the attenuation of lipid peroxidation, platelet aggregation, and capillary permeability. However, further research is called for to gain a better understanding of how quercetin is able to provide these beneficial effects. This manuscript reviewed quercetin’s anti-inflammatory properties in relation to obesity and type 2 diabetes.
Lifting-correction is a technique to restore buildings experiencing uneven settlement, while ensuring the safety and integrity of the main structural system. This study was based on a real ...light-steel building structure and provided a detailed description of scenarios involving uneven settlement and the process of lifting and correction. Additionally, a sophisticated finite element (FE) model was established using the generic FE software ABAQUS, with refined material constitutive models to ensure the accuracy of simulation results. Firstly, the impact of uneven settlement on the structure was examined, including modal and stress field analyses. Different methods of breaking column (BC) and lifting column (LC) were compared and scrutinized to identify optimal approaches and minimize damage and disturbance to the building. Four methods have been proposed and compared, including simultaneously breaking columns, breaking columns with chessboard style, simultaneously lifting columns and lifting columns in multiple stages. The four methods were comprehensively evaluated from the perspectives of stress fields, displacement responses, damage and energy dissipation. The results indicated that after uneven settlement, the eigenvalues and frequencies of the structure decrease, the structure tended to be unstable. Simultaneously, as stress increases, some joints' materials enter the yielding stage, affecting the overall structural stability and safety. When damage occurs in some joints, the structural safety was compromised. The comparison between the two BC methods, including the chessboard style and simultaneously BC methods, it was revealed that the former causes less disturbance to structural initial stress field. The comparison between the two LC methods, including, simultaneously and LC in multiple stages, it was revealed that the latter performs slightly better in terms of stress fields, displacement fields, damage, energy dissipation and internal forces. Therefore, the methods of BC in chessboard style and LC in multiple stages were recommended to use in engineering practice to ensure less structural disturbance. The findings obtained from this study can provide guidance for structural engineers to solve the uneven settlement of buildings.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is currently a global pandemic, and there are limited laboratory studies targeting pathogen resistance. This study aimed to ...investigate the effect of selected disinfection products and methods on the inactivation of SARS-CoV-2 in the laboratory. We used quantitative suspension testing to evaluate the effectiveness of the disinfectant/method. Available chlorine of 250 mg/L, 500 mg/L, and 1000 mg/L required 20 min, 5 min, and 0.5 min to inactivate SARS-CoV-2, respectively. A 600-fold dilution of 17% concentration of di-N-decyl dimethyl ammonium bromide (283 mg/L) and the same concentration of di-N-decyl dimethyl ammonium chloride required only 0.5 min to inactivate the virus efficiently. At 30% concentration for 1 min and 40% and above for 0.5 min, ethanol could efficiently inactivate SARS-CoV-2. Heat takes approximately 30 min at 56 °C, 10 min above 70 °C, or 5 min above 90 °C to inactivate the virus. The chlorinated disinfectants, Di-N-decyl dimethyl ammonium bromide/chloride, ethanol, and heat could effectively inactivate SARS-CoV-2 in the laboratory test. The response of SARS-CoV-2 to disinfectants is very similar to that of SARS-CoV.
In-sensor multi-task learning is not only the key merit of biological visions but also a primary goal of artificial-general-intelligence. However, traditional silicon-vision-chips suffer from large ...time/energy overheads. Further, training conventional deep-learning models is neither scalable nor affordable on edge-devices. Here, a material-algorithm co-design is proposed to emulate human retina and the affordable learning paradigm. Relying on a bottle-brush-shaped semiconducting p-NDI with efficient exciton-dissociations and through-space charge-transport characteristics, a wearable transistor-based dynamic in-sensor Reservoir-Computing system manifesting excellent separability, fading memory, and echo state property on different tasks is developed. Paired with a 'readout function' on memristive organic diodes, the RC recognizes handwritten letters and numbers, and classifies diverse costumes with accuracies of 98.04%, 88.18%, and 91.76%, respectively (higher than all reported organic semiconductors). In addition to 2D images, the spatiotemporal dynamics of RC naturally extract features of event-based videos, classifying 3 types of hand gestures at an accuracy of 98.62%. Further, the computing cost is significantly lower than that of the conventional artificial-neural-networks. This work provides a promising material-algorithm co-design for affordable and highly efficient photonic neuromorphic systems.
Abstract
Discovery of Weyl semimetals has revived interest in Weyl fermions which has not been observed in high energy experiments. It now becomes possible to study, in solids, their exotic ...properties. Extensive photoemission spectroscopy and electrical resistivity experiments have been carried out. However, many other properties remain unexplored. Here we show the thermoelectric signature of the chiral anomaly of Weyl fermions in Cd
3
As
2
under a magnetic field. We observe a strong quadratic suppression of the thermopower when the magnetic field is parallel to the temperature gradient. The quadratic coefficient is nearly twice of that for the electrical conductivity. The thermopower reverses its sign in high fields. We show that all these intriguing observations can be understood in terms of the chiral anomaly of Weyl fermions. Our results reveal the anomalous thermoelectric property of Weyl fermions and provide insight into the chiral anomaly.
A foundation of the modern technology that uses single-crystal silicon has been the growth of high- quality single-crystal Si ingots with diameters up to 12 inches or larger. For many applications of ...graphene, large-area high-quality （ideally of single-crystal） material will be enabling. Since the first growth on copper foil a decade ago, inch-sized single-crystal graphene has been achieved. We present here the growth, in 20 min, of a graphene film of （5 × 50） cm^2 dimension with 〉99% ultra-highly oriented grains. This growth was achieved by： （1） synthesis of metre-sized single-crystal Cu（111） foil as substrate; （2） epitaxial growth of graphene islands on the Cu（1 1 1） surface; （3） seamless merging of such graphene islands into a graphene film with high single crystallinity and （4） the ultrafast growth of graphene film. These achievements were realized by a temperature-gradient-driven annealing technique to produce single-crystal Cu（1 1 1） from industrial polycrystalline Cu foil and the marvellous effects of a continuous oxygen supply from an adjacent oxide. The as-synthesized graphene film, with very few misoriented grains （if any）, has a mobility up to ～23,000 cm^2 V^-1 s^-1 at 4 K and room temperature sheet resistance of ～230 Ω/□. It is very likely that this approach can be scaled up to achieve exceptionally large and high-quality graphene films with single crystallinity, and thus realize various industrial-level applications at a low cost.
•Three ignition devices have run the RDE model successfully.•The initiation process of rotating detonation wave is recorded and analyzed.•The operating characteristic is independent of the ignition ...device.•The operating range of the engine model is determined by series of tests.
An experimental study on a rotating detonation engine model using hydrogen/air mixture as propellant was conducted to analyze the initiation characteristics of detonation wave. Three ignition methods, including the ordinary spark plug, high-energy spark plug and thermal-jet tube, were used in the tests. The initiation process of rotating detonation wave was recorded and analyzed by a high frequency pressure measurement system and high-speed photographs. Operating range of the model engine was determined by series of experiments. Results indicate that the model engine could be successfully run by all the three ignition methods. Although the detonation formation time using spark plugs is quite stochastic, increasing the ignition energy can reduce the formation time of the detonation wave. Among the three ignition methods, thermal-jet provides the shortest detonation formation time. It is also found that the operating characteristic of the model engine is independent of the ignition device in the same operating condition. Three operation modes of the engine model have been observed, which are failed initiation of the detonation, unstable detonation and continuous rotating detonation. The experimental results show that the stable operating range can be extended by increasing the fuel mass flow rate.
Enterprise systems (ES) integrate global goals for the organization and local goals for functional subunits. An organization must arrive at a goal set that directs ES implementation. Constructive ...controversy theory provides direction for methods that arrive at an integrated system solution when original goals may be equivocal. Data from 142 organizations confirm such approaches are effective. The results contribute to our understanding of how ES implementations face goal equivocality and derive a resolution process.
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