We present cosmological parameter constraints using maps from the last
Planck
data release (PR4). In particular, we detail an upgraded version of the cosmic microwave background likelihood,
HiLLiPoP
..., that is based on angular power spectra and relies on a physical modeling of the foreground residuals in the spectral domain. This new version of the likelihood retains a larger sky fraction (up to 75%) and uses an extended multipole range. Using this likelihood, along with low-
ℓ
measurements from
LoLLiPoP
, we derived constraints on ΛCDM parameters that are in good agreement with previous
Planck
2018 results, but with smaller uncertainties by 10% to 20%. We demonstrate that the foregrounds can be accurately described in the spectral domain, with a negligible impact on ΛCDM parameters. We also derived constraints on single-parameter extensions to ΛCDM, including
A
L
, Ω
K
,
N
eff
, and ∑
m
ν
. Noteworthy results from this updated analysis include a lensing amplitude value of
A
L
= 1.039 ± 0.052, which is more closely aligned with theoretical expectations within the ΛCDM framework. Additionally, our curvature measurement, Ω
K
= −0.012 ± 0.010, is now fully consistent with a flat universe and our measurement of
S
8
is closer to the measurements derived from large-scale structure surveys (at the 1.5
σ
level). We also added constraints from PR4 lensing, making this combination the most tightly constrained data set currently available from
Planck
. Additionally, we explored the addition of baryon acoustic oscillation data, which tightens the limits on some particular extensions to the standard cosmology.
In this paper, we study the estimation of the effective number of relativistic species from a combination of cosmic microwave background (CMB) and baryon acoustic oscillations (BAO) data. We vary ...different ingredients of the analysis: the Planck high-ℓ likelihoods, the Boltzmann solvers, and the statistical approaches. The variation of the inferred values gives an indication of an additional systematic uncertainty, which is of the same order of magnitude as the error derived from each individual likelihood. We show that this systematic uncertainty is essentially associated to the assumptions made in the high-ℓ likelihood implementations, in particular for the foreground residuals modellings. We also compare a subset of likelihoods using only the TE power spectra, expected to be less sensitive to foreground residuals.
The new setup of the CODALEMA experiment installed at the Radio Observatory in Nançay, France, is described. It includes broadband active dipole antennas and an extended and upgraded particle ...detector array. The latter gives access to the air shower energy, allowing us to compute the efficiency of the radio array as a function of energy. We also observe a large asymmetry in counting rates between showers coming from the North and the South in spite of the symmetry of the detector. The observed asymmetry can be interpreted as a signature of the geomagnetic origin of the air shower radio emission. A simple linear dependence of the electric field with respect to
v
∧
B is used which reproduces the angular dependencies of the number of radio events and their electric polarity.
Summary
What is known and Objective: The effect of a statin‐based medical intervention on prevention of fatal and non‐fatal stroke recurrence and the incidence of all‐causes mortality have been ...explored previously in aging populations within the scope of clinical trials research. However, such evidence needs to be explored under conditions of routine clinical practice. The objective of this study was to determine whether statin therapy in patients with a first stroke episode reduces the incidence of 6‐year recurrent fatal or non‐fatal stroke and all‐cause mortality in an aging Mediterranean population without known coronary heart disease followed in routine medical practice.
Methods: A retrospective study was carried out using records on death, hospitalizations owing to stroke and history of statin therapy included in the Badalona Serveis Assistencials (BSA) database. The cohort studied consisted of consecutive patients covered by the BSA health provider plan with a first‐ever acute stroke episode during January 2003 until December 2008, for whom there was available information covering the 6‐year follow‐up period. Recurrence rate (RR) and incidence rate (IR) of fatal/non‐fatal stroke and all‐causes mortality were computed. Association with statin therapy was assessed by means of calculation of relative risk (RR) and hazard ratio (HR) using multivariate logistic regression and Cox proportional hazards models controlling for confounding covariates.
Results and Discussion: The cohort comprised a series of 601 consecutive patients 57% men, 75·9 (12·4) years old (88% >60 years). Of these, 32% received statins, which were associated with lower fatal/non‐fatal recurrent stroke RR; 7% vs. 18% adjusted RR = 0·32 (CI: 0·16–0·61), P = 0·001 and lower IR; 16·78 vs. 45·22 events/year‐1000 subjects adjusted HR = 0·35 (0·19–0·64), P = 0·001. Similarly, observed all‐causes mortality was lower in the cohort receiving statins; 11% vs. 16% adjusted RR = 0·29 (CI: 0·08–1·12), P = 0·072, and also mortality rate; 26·09 vs. 36·25 deaths/year‐1000 subjects adjusted HR = 0·23 (0·08–0·67), P = 0·007.
What is new and Conclusions: Statin therapy in patients with first‐ever acute stroke lowers the risk of 6‐year stroke recurrence and improves survival in an aging Mediterranean cohort. These results add additional evidence in routine clinical practice to the observed effects of statins in clinical trials.
The full data set of the NEMO-3 experiment has been used to measure the half-life of the two-neutrino double beta decay of Formula omittedMo to the ground state of Formula omittedRu, Formula omitted ...year. The two-electron energy sum, single electron energy spectra and distribution of the angle between the electrons are presented with an unprecedented statistics of Formula omitted events and a signal-to-background ratio of Formula omitted 80. Clear evidence for the Single State Dominance model is found for this nuclear transition. Limits on Majoron emitting neutrinoless double beta decay modes with spectral indices of Formula omitted, as well as constraints on Lorentz invariance violation and on the bosonic neutrino contribution to the two-neutrino double beta decay mode are obtained.
In this paper, we study the estimation of the effective number of relativistic species from a combination of cosmic microwave background (CMB) and baryon acoustic oscillations (BAO) data. We vary ...different ingredients of the analysis: the
Planck
high-
ℓ
likelihoods, the Boltzmann solvers, and the statistical approaches. The variation of the inferred values gives an indication of an additional systematic uncertainty, which is of the same order of magnitude as the error derived from each individual likelihood. We show that this systematic uncertainty is essentially associated to the assumptions made in the high-
ℓ
likelihood implementations, in particular for the foreground residuals modellings. We also compare a subset of likelihoods using only the TE power spectra, expected to be less sensitive to foreground residuals.
•La elección de la técnica adecuada para la reconstrucción del defecto de tejidos blandos es un desafío terapéutico.•El colgajo de lengüeta medial es una opción comparable a los colgajos ...convencionales para los defectos de tejidos blandos de la cara anterior de la pierna.•La principal ventaja de este colgajo es que no requiere una formación específica en técnicas microquirúrgicas para su realización.
La selección adecuada para la reconstrucción de tejidos blandos en la pierna es un reto terapéutico. A pesar de disponer de varias opciones de reconstrucción, es importante elegir una técnica eficaz y con la menor morbilidad posible de la zona donante.
Demostrar la eficacia terapéutica del colgajo de lengüeta medial en la reconstrucción de tejidos blandos de la pierna, en comparación con los colgajos convencionales.
Estudio de cohorte emparejado por edad. Se seleccionaron 64 pacientes con defectos de tejidos blandos, divididos, de acuerdo a la intervención, en 1)colgajo de lengüeta medial, y 2)colgajos convencionales (sural, sóleo, gastrocnemio), y se les realizó seguimiento hasta el año postoperatorio. Variables de desenlace: tiempo quirúrgico en minutos, cicatrización, tiempo de cicatrización en días, complicaciones.
Los pacientes que fueron sometidos a cirugía con colgajo de lengüeta medial y colgajos convencionales cicatrizaron completamente. El tiempo de cicatrización fue de 16,2±11,2 días en el colgajo de lengüeta y de 16,1±11,2 días en los convencionales, sin diferencias estadísticamente significativas entre los grupos (p=0,89).
El tiempo quirúrgico para los colgajos de lengüeta fue de 225,2±117,8 minutos, y de 191,3±117,2 minutos para los de comparación (p=0,65), sin diferencias estadísticamente significativas. No hubo complicaciones en los colgajos de lengüeta medial.
Los hallazgos sugieren que la técnica de colgajo de lengüeta medial es tan eficaz como la técnica de colgajo convencional, con preservación y cicatrización completa del colgajo y sin ninguna complicación mayor en este grupo estudiado.
Selecting the right technique for lower limb soft tissue reconstruction is a therapeutic challenge. Despite having several reconstruction options, it's important to choose a technique that is effective and with the least possible donor site morbidity.
Demonstrate the therapeutic efficacy of the medial tab flap in soft tissue reconstruction on the leg, compared to conventional flaps.
Cohort study matched by age. 64 patients with soft tissue defects were selected and according to the intervention divided in: group 1)medial tab flap, and group 2)conventional flaps (sural, soleus, gastrocnemius) followed up to one year postoperatively. Outcome variables: surgical time in minutes, healing, healing time in days, complications.
The patients who underwent surgery with medial tab flap and with conventional flaps healed completely. The healing time was 16.2±11.2 days in the tab flap and 16.1±11.2 days in conventional flaps, no statistically significant differences were found between the groups (P=.89).
The surgical time for tab flaps was 225.2±117.8minutes, and 191.3±117.2minutes for the comparison flaps (P=.65), there were no statistically significant differences. There were no complications in the medial tab flaps.
The findings suggest that the medial tab flap technique is as effective as the conventional flap technique, with complete flap survival and healing, and without any major complications in this studied group.
The possibility to probe new physics scenarios of light Majorana neutrino exchange and right-handed currents at the planned next generation neutrinoless double
β
decay experiment SuperNEMO is ...discussed. Its ability to study different isotopes and track the outgoing electrons provides the means to discriminate different underlying mechanisms for the neutrinoless double
β
decay by measuring the decay half-life and the electron angular and energy distributions.
The NEMO-3 results for the double-
β
decay of
150
Nd to the 0
1
+
and 2
1
+
excited states of
150
Sm are reported. The data recorded during 5.25 year with 36.6 g of the isotope
150
Nd are used in the ...analysis. The signal of the
2
ν
β
β
transition to the 0
1
+
excited state is detected with a statistical significance exceeding 5
σ
. The half-life is measured to be
T
1
/
2
2
ν
β
β
(
0
1
+
)
=
1
.
11
-
0.14
+
0.19
stat
-
0.15
+
0.17
syst
×
10
20
year, which is the most precise value that has been measured to date. 90% confidence-level limits are set for the other decay modes. For the
2
ν
β
β
decay to the 2
1
+
level the limit is
T
1
/
2
2
ν
β
β
(
2
1
+
)
>
2.42
×
10
20
year
. The limits on the
0
ν
β
β
decay to the 0
1
+
and 2
1
+
levels of
150
Sm are significantly improved to
T
1
/
2
0
ν
β
β
(
0
1
+
)
>
1.36
×
10
22
year
and
T
1
/
2
0
ν
β
β
(
2
1
+
)
>
1.26
×
10
22
year
.
Abstract The NEMO-3 results for the double- $$\beta $$ β decay of $$^{150}$$ 150 Nd to the 0 $$^+_1$$ 1 + and 2 $$^+_1$$ 1 + excited states of $$^{150}$$ 150 Sm are reported. The data recorded during ...5.25 year with 36.6 g of the isotope $$^{150}$$ 150 Nd are used in the analysis. The signal of the $$2\nu \beta \beta $$ 2 ν β β transition to the 0 $$^+_1$$ 1 + excited state is detected with a statistical significance exceeding 5 $$\sigma $$ σ . The half-life is measured to be $$T_{1/2}^{2\nu \beta \beta }(0^+_1) = \left 1.11 ^{+0.19}_{-0.14} \,\left( \hbox {stat}\right) ^{+0.17}_{-0.15}\,\left( \hbox {syst}\right) \right \times 10^{20}$$ T 1 / 2 2 ν β β ( 0 1 + ) = 1 . 11 - 0.14 + 0.19 stat - 0.15 + 0.17 syst × 10 20 year, which is the most precise value that has been measured to date. 90% confidence-level limits are set for the other decay modes. For the $$2\nu \beta \beta $$ 2 ν β β decay to the 2 $$^+_1$$ 1 + level the limit is $$T^{2\nu \beta \beta }_{1/2}(2^+_1) > 2.42 \times 10^{20}~\hbox {year}$$ T 1 / 2 2 ν β β ( 2 1 + ) > 2.42 × 10 20 year . The limits on the $$0\nu \beta \beta $$ 0 ν β β decay to the 0 $$^+_1$$ 1 + and 2 $$^+_1$$ 1 + levels of $$^{150}$$ 150 Sm are significantly improved to $$T_{1/2}^{0\nu \beta \beta }(0^+_1) > 1.36 \times 10^{22}~\hbox {year}$$ T 1 / 2 0 ν β β ( 0 1 + ) > 1.36 × 10 22 year and $$T_{1/2}^{0\nu \beta \beta }(2^+_1) > 1.26 \times 10^{22}~\hbox {year}$$ T 1 / 2 0 ν β β ( 2 1 + ) > 1.26 × 10 22 year .
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