This study systematically reviews prospective and retrospective cohort studies evaluating the risk of hip fracture following stroke. Stroke survivors are at high risk of hip fracture and had a ...1.5-fold increased risk compared to stroke-free men and women of the same age. Hip fracture often occurs in ageing and female stroke patients. We performed a meta-analysis to summarize evidence from prospective and retrospective cohort studies about the risk of hip fracture following stroke. We identified English and non-English publications in MEDLINE and EMBASE using stroke and fracture as keywords to 31 December 2015. The data of the incidence of hip fracture were extracted to calculate raw incident rate in stroke survivors as well as risk of hip fractures in strokes comparing populations using a random-effects model. Subgroup analyses were performed to identify the potential influence of some factors. Six prospective and seven retrospective cohort studies were included, involving 512,214 stroke patients with 22,559 hip fractures. The pooled prevalence of hip fractures was 4.87 % (95 % CI, 4.05 to 5.68 %) in stoke patients. We conducted subgroup analysis according to sex, age, duration of follow-up, study design, and region, which showed that female (vs. male) stroke patients older than 70 years (vs. those less than 70 years) and duration of follow-up more than 2 years (vs. those less than 2 years) have higher proportions of hip fractures. Four studies showed that stroke patients had a significantly higher risk of hip fracture compared with the general population, while the other study had a non-significant higher risk. The overall prevalence of hip fracture was 3.28 % (3431 of 104,646) in stroke patients and 2.83 % (36,493 of 1,287,726) in general population, respectively, and the unadjusted combined relative risk of hip fracture was 1.54 (95 % CI, 1.06–2.25). Hip fractures often occur in ageing and female stroke patients.
ABSTRACT
We report the phase-connected timing ephemeris, polarization pulse profiles, Faraday rotation measurements, and Rotating-Vector-Model (RVM) fitting results of 12 millisecond pulsars (MSPs) ...discovered with the Five-hundred-meter Aperture Spherical radio Telescope (FAST) in the Commensal Radio Astronomy FAST survey (CRAFTS). The timing campaigns were carried out with FAST and Arecibo over 3 yr. 11 of the 12 pulsars are in neutron star–white dwarf binary systems, with orbital periods between 2.4 and 100 d. 10 of them have spin periods, companion masses, and orbital eccentricities that are consistent with the theoretical expectations for MSP–Helium white dwarf (He WD) systems. The last binary pulsar (PSR J1912−0952) has a significantly smaller spin frequency and a smaller companion mass, the latter could be caused by a low orbital inclination for the system. Its orbital period of 29 d is well within the range of orbital periods where some MSP–He WD systems have shown anomalous eccentricities, however, the eccentricity of PSR J1912−0952 is typical of what one finds for the remaining MSP–He WD systems.
Using recently published, high-precision
π
+
π
−
cross section data by the BABAR experiment from the analysis of
e
+
e
−
events with high-energy photon radiation in the initial state, we reevaluate ...the lowest order hadronic contribution
to the anomalous magnetic moment of the muon. We employ newly developed software featuring improved data interpolation and averaging, more accurate error propagation and systematic validation. With the new data, the discrepancy between the
e
+
e
−
- and
τ
-based results for the dominant two-pion mode reduces from previously 2.4
σ
to 1.5
σ
in the dispersion integral, though significant local discrepancies in the spectra persist. We obtain for the
e
+
e
−
-based evaluation
, where the error accounts for all sources. The full Standard Model prediction of
a
μ
differs from the experimental value by 3.2
σ
.
A golden age for heavy-quarkonium physics dawned a decade ago, initiated by the confluence of exciting advances in quantum chromodynamics (QCD) and an explosion of related experimental activity. The ...early years of this period were chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in 2004, which presented a comprehensive review of the status of the field at that time and provided specific recommendations for further progress. However, the broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles could only be partially anticipated. Since the release of the YR, the BESII program concluded only to give birth to BESIII; the
B
-factories and CLEO-c flourished; quarkonium production and polarization measurements at HERA and the Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the deconfinement regime. All these experiments leave legacies of quality, precision, and unsolved mysteries for quarkonium physics, and therefore beg for continuing investigations at BESIII, the LHC, RHIC, FAIR, the Super Flavor and/or Tau–Charm factories, JLab, the ILC, and beyond. The list of newly found conventional states expanded to include
h
c
(1
P
),
χ
c
2
(2
P
),
, and
η
b
(1
S
). In addition, the unexpected and still-fascinating
X
(3872) has been joined by more than a dozen other charmonium- and bottomonium-like “
XYZ
” states that appear to lie outside the quark model. Many of these still need experimental confirmation. The plethora of new states unleashed a flood of theoretical investigations into new forms of matter such as quark–gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the spectroscopy, decays, production, and in-medium behavior of
,
, and
bound states have been shown to validate some theoretical approaches to QCD and highlight lack of quantitative success for others. Lattice QCD has grown from a tool with computational possibilities to an industrial-strength effort now dependent more on insight and innovation than pure computational power. New effective field theories for the description of quarkonium in different regimes have been developed and brought to a high degree of sophistication, thus enabling precise and solid theoretical predictions. Many expected decays and transitions have either been measured with precision or for the first time, but the confusing patterns of decays, both above and below open-flavor thresholds, endure and have deepened. The intriguing details of quarkonium suppression in heavy-ion collisions that have emerged from RHIC have elevated the importance of separating hot- and cold-nuclear-matter effects in quark–gluon plasma studies. This review systematically addresses all these matters and concludes by prioritizing directions for ongoing and future efforts.
The evolutions of MHD instability behaviors and enhancement of both electrostatic and electromagnetic turbulence towards the plasma disruption have been clearly observed in the HL-2A plasmas. Two ...types of plasma disruptive discharges have been investigated for similar equilibrium parameters: one with a distinct stage of a small central temperature collapse (Formula: see text 5-10%) around 1 millisecond before the thermal quench (TQ), while the other without. For both types, the TQ phase is preceded by a rotating 2/1 tearing mode, and it is the development of the cold bubble from the inner region of the 2/1 island O-point along with its inward convection that causes the massive energy loss. In addition, the micro-scale turbulence, including magnetic fluctuations and density fluctuations, increases before the small collapse, and more significantly towards the TQ. Also, temperature fluctuations measured by electron cyclotron emission imaging enhances dramatically at the reconnection site and expand into the island when approaching the small collapse and TQ, and the expansion is more significant close to the TQ. The observed turbulence enhancement near the X-point cannot be fully interpreted by the linear stability analysis by GENE. Evidences suggest that nonlinear effects, such as the reduction of local Formula: see text shear and turbulence spreading, may play an important role in governing turbulence enhancement and expansion. These results imply that the turbulence and its interaction with the island facilitate the stochasticity of the magnetic flux and formation of the cold bubble, and hence, the plasma disruption.
Objective
Chronic inflammation is recognized as a risk factor for colorectal cancer (CRC) development. Baicalin (BI), a major constituent in an anti-inflammatory herb
Scutellaria baicalensis
, can be ...biotransformed into baicalein (BE) by the intestinal microbiota. We evaluated the anti-inflammation and anti-CRC effects of the metabolite BE.
Methods
The in vitro biotransformation by human intestinal microbiota from BI into BE has been determined with HPLC. Using a gut-specific
Apc
Min/
+
mouse model, the effects of oral BE on the life span, organ index, and tumor multiplicity were evaluated. The expressions of inflammatory cytokines were determined using ELISA. To verify the in vivo data, the anti-inflammatory and antiproliferative effects of BE were determined with an in vitro cell model.
Results
HPLC analysis showed that BI was quickly transformed into BE by the intestinal microbiota. Oral BE (30 mg/kg/day) significantly increased the life span, from 125.2 to 218.4 days (
P
< 0.01%). BE treatment also decreased intestine index and increased spleen index. Compared with the model group, following BE treatment, tumor numbers were significantly reduced in the small intestine and colon (
P
< 0.01,
P
< 0.05, respectively). In the gut tissues, BE treatment significantly reduced inflammatory cytokine levels such as IL-1β, IL-2, IL-6, IL-10, G-CSF, and GM-CSF. In vitro data supported our in vivo results that the anti-CRC effects of BE were via the inhibition of gut inflammation and induction of cancer cell death.
Conclusion
Our results suggest that the parent compound BI can be quickly converted into its microbial metabolite BE, which has stronger bioactive effects than BI. Baicalein is an active chemopreventive metabolite for inflammatory associated CRC.
(ProQuest: ... denotes formulae and/or non-USASCII text omitted; see image) An update of the ALEPH non-strange spectral functions from hadronic ... decays is presented. Compared to the 2005 ALEPH ...publication, the main improvement is related to the use of a new method to unfold the measured mass spectra from detector effects. This procedure also corrects a previous problem in the correlations between the unfolded mass bins. Results from QCD studies and for the evaluation of the hadronic vacuum polarisation contribution to the anomalous muon magnetic moment are derived using the new spectral functions. They are found in agreement with published results based on the previous set of spectral functions.
ABSTRACT
The follow-up timing observations were carried out for 24 pulsars discovered with the Five-hundred-meter Aperture Spherical radio Telescope (FAST) in Commensal Radio Astronomy FAST Survey. ...We report their phase-connected timing ephemeris, polarization pulse profiles, and Faraday rotation measurements. With their spin periods spanning from 2.995 ms to 4.34 s, their period derivatives were determined to spread between 7.996(8) × 10−21 and 9.83(3) × 10−15 s s−1, which imply that they have characteristic ages from 1.97 × 106 to 5.93 × 109 yr. It is inferred that PSRs J0211+4235 and J0518+2431 are beyond the ‘traditional death line’. PSR J0211+4235 is beyond the ‘death valley’. The death line model of Zhang et al. also cannot explain the radio presence of PSR J0211+4235. This suggests that radiation theory needs to be improved. Besides, ten of the 22 canonical pulsars show nulling phenomena. Moreover, PSR J1617+1123 exhibits variation of emission and J0540+4542 shows subpulse drifting. The DM of five pulsars is larger than the estimated by the YMW16 electron density model, which could suggest that electron density models need updates for higher Galactic latitude regions. PSRs J0447+2447 and J1928−0548 are isolated millisecond pulsars. With their flux densities spanning from 5(1)–553(106) μJy, some of these new pulsars found by FAST are distant, dim, and low-$\dot{E}$ ones and are suitable for testing pulsar emission theories.
China is the second largest energy consumer in the world. This paper reviews the production and consumption of traditional and renewable energy in China over the past three decades. It also presents ...an overview on the research and development of renewable energy, such as solar, biomass, geothermal, ocean and wind energy in China. Study indicated that the usage of renewable energy in China shows a promising prospect in the near future, of which biomass is found to be one of the most promising renewable energy resources that have great potential for development in China.
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