A novel observable measuring the CP asymmetry in multi-body decays of heavy mesons, which is called the forward-backward asymmetry induced CP asymmetry (FBI-CPA), ACPFB, is introduced. This ...observable has the dual advantages that 1) it can isolate the CP asymmetry associated with the interference of the S- and P-wave amplitude from that associated with the S- or P-wave amplitude alone; 2) it can effectively almost double the statistics comparing to the conventionally defined regional CP asymmetry. We also suggest to perform the measurements of FBI-CPA in some three-body decay channels of charm and beauty mesons.
Since its emergence in December 2019, corona virus disease 2019 (COVID-19) has impacted several countries, affecting more than 90 thousand patients and making it a global public threat. The routes of ...transmission are direct contact, and droplet and possible aerosol transmissions. Due to the unique nature of dentistry, most dental procedures generate significant amounts of droplets and aerosols, posing potential risks of infection transmission. Understanding the significance of aerosol transmission and its implications in dentistry can facilitate the identification and correction of negligence in daily dental practice. In addition to the standard precautions, some special precautions that should be implemented during an outbreak have been raised in this review.
Disordered systems like liquids, gels, glasses, or granular materials are not only ubiquitous in daily life and in industrial applications, but they are also crucial for the mechanical stability of ...cells or the transport of chemical and biological agents in living organisms. Despite the importance of these systems, their microscopic structure is understood only on a rudimentary level, thus in stark contrast to the case of gases and crystals. Since scattering experiments and analytical calculations usually give only structural information that is spherically averaged, the three-dimensional (3D) structure of disordered systems is basically unknown. Here, we introduce a simple method that allows probing of the 3D structure of such systems. Using computer simulations, we find that hard sphere-like liquids have on intermediate and large scales a simple structural order given by alternating layers with icosahedral and dodecahedral symmetries, while open network liquids like silica have a structural order with tetrahedral symmetry. These results show that liquids have a highly nontrivial 3D structure and that this structural information is encoded in nonstandard correlation functions.
Abstract This study examines the interconnectedness between Green Market Orientation (GMO) and Green Knowledge Management (GKM) in connection to Green Competitive Advantage (GCA) within Chinese green ...businesses. This research also focuses on the mediating influence of Green Creativity (GC). Drawing on the Knowledge-Based View (KBV), we examine how GMOs and GKM improve enterprises’ green creativity and subsequent green competitive advantage. Using a comprehensive survey of 325 environmentally conscious Chinese companies and an advanced PLS-SEM analysis, our findings offer several important insights. Our findings reveal that GMOs substantially affect both GC and GCA, highlighting their crucial role in fostering a company’s innovative green capabilities and competitive position. Concurrently, GKM positively affects GC and GCA, emphasizing the importance of effectively using and leveraging green knowledge within businesses. Furthermore, we observe the mediating role of GC in the relationships between GMO and GCA, as well as GKM and GCA. This finding underscores the need to promote GC to maximize the advantages of market orientation and knowledge management in attaining a green competitive advantage. These results not only add to the existing KBV theoretical framework, but they also have important implications for managers because they show how important it is to fully incorporate green practices into an organization’s strategy in order to gain a sustainable competitive advantage.
Linguistic large-scale group decision making (LGDM) problems are more and more common nowadays. In such problems a large group of decision makers are involved in the decision process and elicit ...linguistic information that are usually assessed in different linguistic scales with diverse granularity because of decision makers' distinct knowledge and background. To keep maximum information in initial stages of the linguistic LGDM problems, the use of multigranular linguistic distribution assessments seems a suitable choice, however, to manage such multigranular linguistic distribution assessments, it is necessary the development of a new linguistic computational approach. In this paper, it is proposed a novel computational model based on the use of extended linguistic hierarchies, which not only can be used to operate with multigranular linguistic distribution assessments but also can provide interpretable linguistic results to decision makers. Based on this new linguistic computational model, an approach to linguistic large-scale multiattribute group decision making is proposed and applied to a talent selection process in universities.
Since the outbreak in late December 2019 in Wuhan, China, coronavirus disease-2019 (COVID-19) has become a global pandemic. We analyzed and compared the clinical, laboratory, and radiological ...characteristics between survivors and non-survivors and identify risk factors for mortality.
Clinical and laboratory variables, radiological features, treatment approach, and complications were retrospectively collected in two centers of Hubei province, China. Cox regression analysis was conducted to identify the risk factors for mortality.
A total of 432 patients were enrolled, and the median patient age was 54 years. The overall mortality rate was 5.09% (22/432). As compared with the survivor group (n = 410), those in the non-survivor group (n = 22) were older, and they had a higher frequency of comorbidities and were more prone to suffer from dyspnea. Several abnormal laboratory variables indicated that acute cardiac injury, hepatic damage, and acute renal insufficiency were detected in the non-survivor group. Non-surviving patients also had a high computed tomography (CT) score and higher rate of consolidation. The most common complication causing death was acute respiratory distress syndrome (ARDS) (18/22, 81.8%). Multivariate Cox regression analysis revealed that hemoglobin (Hb) <90 g/L (hazard ratio, 10.776; 95% confidence interval, 3.075-37.766; p<0.0001), creatine kinase (CK-MB) >8 U/L (9.155; 2.424-34.584; p = 0.001), lactate dehydrogenase (LDH) >245 U/L (5.963; 2.029-17.529; p = 0.001), procalcitonin (PCT) >0.5 ng/ml (7.080; 1.671-29.992; p = 0.008), and CT score >10 (39.503; 12.430-125.539; p<0.0001) were independent risk factors for the mortality of COVID-19.
Low Hb, high LDH, PCT, and CT score on admission were the predictors for mortality and could assist clinicians in early identification of poor prognosis among COVID-19 patients.
Biosensors are considered a popular technology to rapidly detect targets, and are generally composed of biorecognition molecules that specifically capture analytes and signal elements ...
Both Global Positioning System (GPS) measurements and studies of Late Quaternary faulting are consistent with a slip rate of ∼10 mm/yr along the central segment of the Altyn Tagh Fault and a ...systematic decrease in that rate toward the eastern end of the fault. Dates of terraces above and below laterally offset terrace risers yield bounds on Quaternary slip rates that range from those that agree with GPS measurements to values as much as three times faster. We argue that offset terrace risers that are protected by topography upstream of them are more closely dated by the age of the upper terrace than by that of the lower terrace. In some cases, valleys upstream of the fault have been incised into bedrock, and few if any terrace risers can be seen within the valleys. Such streams debouch onto alluviated floodplains or fans that become incised, presumably during climate changes, to create terrace risers. The terrace risers are then displaced so that they lie downslope from bedrock ridges on the upstream side of the fault, and thus the risers become protected from further incision. In such cases, dates of upper terraces should more closely approximate the ages of the risers than those of lower terraces. Such dates yield slip rates of ∼10 mm/yr in the central segment of the fault and decreasing rates eastward. Although we cannot with certainty rule out the higher slip rates along the Altyn Tagh Fault, our analysis does show that viable interpretations consistent with GPS measurements are more likely, at least along some segments of the fault. Not only do these rates support the view that the Tibetan Plateau deforms internally by slip on a distributed network of faults in the shallow brittle crust, and hence behaves as a continuum at depth, but the gradual decrease toward the east also shows that the Altyn Tagh Fault does not separate two effectively rigid lithospheric plates. Correspondingly, the relatively low slip rate and the eastward decrease in slip rate suggest that the Altyn Tagh Fault does not transfer a significant portion of the convergence between India and Asia into northeastward extrusion of the Tibetan Plateau. Thus, large‐scale extrusion of crustal material in India's path into Eurasia seems to be limited largely to the confines of the Tibetan Plateau.
Diabetic retinopathy (DR) is a serious diabetic complication caused by both environmental and genetic factors. Molecular mechanisms of DR may lead to the discovery of reliable prognostic indicators. ...The current study aimed to clarify the mechanism of microRNA-183 (miR-183) in DR in relation to the PI3K/Akt/VEGF signaling pathway. Microarray-based gene expression profiling of DR was used to identify the differentially expressed genes. Sprague-Dawley rats were used for the establishment of DR models, and then miR-183 was altered by mimic or inhibitor or
was downregulated by siRNA to explore the regulatory mechanism of miR-183 in DR. Furthermore, the expression of miR-183, CD34, endothelial nitric oxide synthase (eNOS),
and the PI3K/Akt/VEGF signaling pathway-related genes as well as reactive oxygen species (ROS) level was determined, and the relationship between miR-183 and
was also verified. Cell growth, cell apoptosis, and angiogenesis were determined. Microarray analysis revealed the involvement of miR-183 in DR via the PI3K/Akt/VEGF signaling pathway by targeting
. Upregulated miR-183 and downregulated
were observed in retinal tissues of DR rats. miR-183 overexpression activated the PI3K/Akt/VEGF signaling pathway, upregulated CD34, eNOS, and ROS, and inhibited
was confirmed as a target gene of miR-183. miR-183 overexpression or
knockdown promoted cell growth and tube formation while it suppressed cell apoptosis of vascular endothelial cells in DR rats. In this study, we demonstrated that miR-183 silencing inhibiting cell growth and tube formation in vascular endothelial cells of DR rats via the PI3K/Akt/VEGF signaling pathway by upregulating
.
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