Recently, A2 B3 type strong spin orbital coupling compounds such as Bi2 Te3 , Bi2 Se3 and Sb2 Te3 were theoretically predicated to be topological insulators and demonstrated through experimental ...efforts. The counterpart compound Sb2 Se3 on the other hand was found to be topological trivial, but further theoretical studies indicated that the pressure might induce Sb2 Se3 into a topological nontrivial state. Here, we report on the discovery of superconductivity in Sb2 Se3 single crystal induced via pressure. Our experiments indicated that Sb2 Se3 became superconductive at high pressures above 10 GPa proceeded by a pressure induced insulator to metal like transition at ~3 GPa which should be related to the topological quantum transition. The superconducting transition temperature (TC ) increased to around 8.0 K with pressure up to 40 GPa while it keeps ambient structure. High pressure Raman revealed that new modes appeared around 10 GPa and 20 GPa, respectively, which correspond to occurrence of superconductivity and to the change of TC slop as the function of high pressure in conjunction with the evolutions of structural parameters at high pressures.
Background
Chronic sinusitis (CRS) is a common otorhinolaryngologic disease that is frequently encountered in everyday practice, but there is a lack of precise data regarding the prevalence of CRS in ...developing countries. We performed a national investigation in China to determine the prevalence and associated factors of CRS.
Methods
We conducted a cross‐sectional investigation in 2012. A stratified four‐stage sampling method was used to select participants randomly from seven cities in mainland China. All participants were interviewed face‐to‐face via a standardized questionnaire. Unconditional logistic regression analyses were conducted to examine the association between smoking and sinusitis after adjusting for socio‐demographic factors.
Results
This study included a total of 10 636 respondents from seven cities. The overall prevalence of CRS was 8.0% and ranged from 4.8% to 9.7% in seven centres. Chronic sinusitis affected approximately 107 million people in mainland China. Chronic sinusitis was particularly prevalent among people with specific medical conditions, including allergic rhinitis, asthma, chronic obstructive pulmonary disease and gout. The prevalence was slightly higher among males (8.79%) than females (7.28%) (P = 0.004), and the prevalence varied by age group, ethnicity and marital status and education (P < 0.05), but not by household per capita income or living space (P > 0.05). Both second‐hand tobacco smoke and active smoking were independent risk factors for CRS (P = 0.001).
Conclusions
Chronic sinusitis is an important public health problem in China. Our study provides important information for the assessment of the economic burden of CRS and the development and promotion of public health policies associated with CRS particularly in developing countries.
In this paper, the torque production of fractional-slot concentrated-winding (FSCW) permanent-magnet synchronous machines (PMSMs) is analyzed from the perspective of the air-gap field harmonics ...modulation accounting for slotting effect. It is found that the average torque of FSCW PMSM is produced by both the principle of conventional PMSM and the magnetic gearing effect. A finite-element analysis (FEA) based equivalent current sheet model and harmonic restoration method is first used in FSCW PM machines with different slot-pole number combinations to quantify the respective contribution of the conventional PMSM and the magnetic gearing effect to the average torque. The influence of slot opening on the magnetic gearing effect, cogging torque, and torque ripple is analyzed. The results show that the magnetic gearing effect makes a nonignorable contribution to the average torque when a large slot opening stator is used. The expression of the gear ratio in FSCW PMSMs is derived. The influence of gear ratio on the contribution of the magnetic gearing effect to the total torque is investigated by FEA. The FEA-predicted torques are validated by experiments on the prototypes.
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•Application of the phase field (PP) to microcracking in concrete microstructures.•Crack initiation and propagation in complex voxel-based models of microstructures.•An enhanced ...algorithm within PP is proposed to increase the load increments.
In this work, crack initiation and propagation in 2D and 3D highly heterogeneous materials models, such as those obtained by micro-CT imagery of cementitious materials, is investigated for the first time by means of the phase field method. A shifted strain split operator algorithm is proposed to handle unilateral contact within cracks in a very efficient manner. The various advantages of the phase field method for voxel-based models are discussed. More specifically, we show that the resolution related to the initial image and thus to meshes for discretizing the same microstructure does not significantly affect the simulated crack path.
Ciprofol is a newly developed intravenous sedative-hypnotic drug. The objective of the study was to prove whether ciprofol was non-inferior to propofol for the successful induction of general ...anesthesia. The ideal post-induction sedation level was assessed by comparing patients' clinical symptoms and their hemodynamic effects in responding to noxious stimuli, mostly tracheal intubation and bispectral index (BIS) alterations following ciprofol/propofol administration.
In this multi-center, randomized, double-blind phase 3 trial, selective surgery patients were randomly assigned in a 1:1 ratio to either ciprofol 0.4 mg/kg (n = 88) or propofol 2.0 mg/kg (n = 88) groups. The primary endpoint was the percentage of patients with successful anesthesia inductions. Secondary endpoints included the times to successful induction of general anesthesia and loss of the eyelash reflex, changes in BIS, as well as safety indicators.
The anesthesia induction success rates for both ciprofol 0.4 mg/kg and propofol 2 mg/kg groups were 100.0%, with a 95% CI lower success limit of -4.18% difference between the two groups, indicating that ciprofol was non-inferior to propofol. For secondary outcomes, the average time to successful anesthesia and loss of the eyelash reflex were 0.91 min and 0.80 min for ciprofol and 0.80 min and 0.71 min for propofol, respectively. The pattern of BIS changes with ciprofol was similar to propofol and stable during the anesthesia maintenance period. Safety was comparable with 88.6% TEAEs in the ciprofol group compared to 95.5% in the propofol group. The incidence of injection pain was significantly lower in the ciprofol group compared to the propofol group (6.8% vs. 20.5%, p < 0.05). In addition, the patients treated with ciprofol had a lesser increase in blood pressure and heart rate, and fewer cases with BIS > 60 within 15 min of intravenous administration, which indicated that ciprofol may provide a better ideal sedation level during the post-induction period under an equivalent dosing regimen to propofol.
Ciprofol for patients undergoing selective surgery is a new option for the induction of general anesthesia.
In this paper, stator/rotor pole combinations, winding configurations, and electromagnetic performance of novel variable flux reluctance machines (VFRMs), which employ a doubly salient structure ...similar to switched reluctance machines (SRMs) but with stator-located dc field windings, are investigated. VFRMs with 12 stator poles are taken as examples to illustrate the method for determining the winding connections and winding factors. The back-electromotive force (EMF), self- and mutual inductances, cogging torque, static torque, torque ripple, and unbalanced magnetic force (UMF) are investigated by finite-element analyses. It is found that many stator/rotor pole combinations, i.e., 12/8 (which may be derived from the conventional three-phase SRM), 12/10, 12/11, 12/13, and 12/14, are feasible for the 12-stator-pole VFRMs. Among these pole number combinations, the 10- and 14-rotor-pole VFRMs can eliminate the inherent UMF in 6/5 and 6/7 VFRMs and exhibit more sinusoidal back-EMF waveforms and have higher torque density than an 8-rotor-pole VFRM, whereas the 11- and 13-rotor-pole VFRMs exhibit similar torque density as the 10- and 14-rotor-pole VFRMs, but with negligible cogging torque and torque ripple, albeit with UMF. Five prototype VFRMs with 12 stator poles and different rotor poles have been designed, manufactured, and tested to verify the analyses.
This paper reviews the relative merits of induction, switched reluctance, and permanent-magnet (PM) brushless machines and drives for application in electric, hybrid, and fuel cell vehicles, with ...particular emphasis on PM brushless machines. The basic operational characteristics and design requirements, viz. a high torque/power density, high efficiency over a wide operating range, and a high maximum speed capability, as well as the latest developments, are described. Permanent-magnet brushless dc and ac machines and drives are compared in terms of their constant torque and constant power capabilities, and various PM machine topologies and their performance are reviewed. Finally, methods for enhancing the PM excitation torque and reluctance torque components and, thereby, improving the torque and power capability, are described
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