The Atacama Large Millimeter Array (ALMA) Large Program to INvestigate CII at Early times (ALPINE) targets the CII 158
μ
m line and the far-infrared continuum in 118 spectroscopically confirmed ...star-forming galaxies between
z
= 4.4 and
z
= 5.9. It represents the first large CII statistical sample built in this redshift range. We present details regarding the data processing and the construction of the catalogs. We detected 23 of our targets in the continuum. To derive accurate infrared luminosities and obscured star formation rates (SFRs), we measured the conversion factor from the ALMA 158
μ
m rest-frame dust continuum luminosity to the total infrared luminosity (
L
IR
) after constraining the dust spectral energy distribution by stacking a photometric sample similar to ALPINE in ancillary single-dish far-infrared data. We found that our continuum detections have a median
L
IR
of 4.4 × 10
11
L
⊙
. We also detected 57 additional continuum sources in our ALMA pointings. They are at a lower redshift than the ALPINE targets, with a mean photometric redshift of 2.5 ± 0.2. We measured the 850
μ
m number counts between 0.35 and 3.5 mJy, thus improving the current interferometric constraints in this flux density range. We found a slope break in the number counts around 3 mJy with a shallower slope below this value. More than 40% of the cosmic infrared background is emitted by sources brighter than 0.35 mJy. Finally, we detected the CII line in 75 of our targets. Their median CII luminosity is 4.8 × 10
8
L
⊙
and their median full width at half maximum is 252 km s
−1
. After measuring the mean obscured SFR in various CII luminosity bins by stacking ALPINE continuum data, we find a good agreement between our data and the local and predicted SFR–
L
CII
relations.
We unveil the complex shape of a proto-supercluster at z ∼ 2.45 in the COSMOS field exploiting the synergy of both spectroscopic and photometric redshifts. Thanks to the spectroscopic redshifts of ...the VIMOS Ultra-Deep Survey (VUDS), complemented by the zCOSMOS-Deep spectroscopic sample and high-quality photometric redshifts, we compute the three-dimensional (3D) overdensity field in a volume of ∼100 × 100 × 250 comoving Mpc3 in the central region of the COSMOS field, centred at z ∼ 2.45 along the line of sight. The method relies on a two-dimensional (2D) Voronoi tessellation in overlapping redshift slices that is converted into a 3D density field, where the galaxy distribution in each slice is constructed using a statistical treatment of both spectroscopic and photometric redshifts. In this volume, we identify a proto-supercluster, dubbed “Hyperion” for its immense size and mass, which extends over a volume of ∼60 × 60 × 150 comoving Mpc3 and has an estimated total mass of ∼4.8 × 1015 M⊙. This immensely complex structure contains at least seven density peaks within 2.4 ≲ z ≲ 2.5 connected by filaments that exceed the average density of the volume. We estimate the total mass of the individual peaks, Mtot, based on their inferred average matter density, and find a range of masses from ∼0.1 × 1014 M⊙ to ∼2.7 × 1014 M⊙. By using spectroscopic members of each peak, we obtain the velocity dispersion of the galaxies in the peaks, and then their virial mass Mvir (under the strong assumption that they are virialised). The agreement between Mvir and Mtot is surprisingly good, at less than 1−2σ, considering that (almost all) the peaks are probably not yet virialised. According to the spherical collapse model, these peaks have already started or are about to start collapsing, and they are all predicted to be virialised by redshift z ∼ 0.8−1.6. We finally perform a careful comparison with the literature, given that smaller components of this proto-supercluster had previously been identified using either heterogeneous galaxy samples (Lyα emitters, sub-mm starbursting galaxies, CO emitting galaxies) or 3D Lyα forest tomography on a smaller area. With VUDS, we obtain, for the first time across the central ∼1 deg2 of the COSMOS field, a panoramic view of this large structure, that encompasses, connects, and considerably expands in a homogeneous way on all previous detections of the various sub-components. The characteristics of this exceptional proto-supercluster, its redshift, its richness over a large volume, the clear detection of its sub-components, together with the extensive multi-wavelength imaging and spectroscopy granted by the COSMOS field, provide us the unique possibility to study a rich supercluster in formation.
Using spectroscopic observations taken for the Visible Multi-Object Spectrograph (VIMOS) Ultra-Deep Survey (VUDS) we report here on the discovery of PCl J1001+0220, a massive proto-cluster of ...galaxies located at zspec ~ 4.57 in the COSMOS field. With nine spectroscopic members, the proto-cluster was initially detected as a ~12σ spectroscopic overdensity of typical star-forming galaxies in the blind spectroscopic survey of the early universe (2 < z ≲ 6) performed by VUDS. It was further mapped using a new technique developed which statistically combines spectroscopic and photometric redshifts, the latter derived from a recent compilation of incredibly deep multi-band imaging performed on the COSMOS field. Through various methods, the descendant mass of PCl J1001+0220 is estimated to be log (Mh/M⊙)z=0 $\log(\mathcal{M}_{h}/\mathcal{M}_{\odot})_{z=0}$log(Mh/M⊙)z=0 ~ 14.5–15 with a large amount of mass apparently already in place at z ~ 4.57. An exhaustive comparison was made between the properties of various spectroscopic and photometric member samples and matched samples of galaxies inhabiting less dense environments at the same redshifts. Tentative evidence is found for a fractional excess of older galaxies more massive in their stellar content amongst the member samples relative to the coeval field, an observation which suggests the pervasive early onset of vigorous star formation for proto-cluster galaxies. No evidence is found for the differences in the star formation rates (SFRs) of member and coeval field galaxies either through estimating by means of the rest-frame ultraviolet or through separately stacking extremely deep Very Large Array 3 GHz imaging for both samples. Additionally, no evidence for pervasive strong active galactic nuclei (AGN) activity is observed in either environment. Analysis of Hubble Space Telescope images of both sets of galaxies as well as their immediate surroundings provides weak evidence for an elevated incidence of galaxy–galaxy interaction within the bounds of the proto-cluster. The stacked and individual spectral properties of the two samples are compared, with a definite suppression of Lyα seen in the average member galaxy relative to the coeval field ( fesc, Lyα = 1.8−1.7+0.3 $f_{esc, \, \textrm{Ly}\alpha} = 1.8^{+0.3}_{-1.7}$fesc, Lyα=1.8−1.7+0.3% and 4.0−0.8+1.0 $4.0^{+1.0}_{-0.8}$4.0−0.8+1.0%, respectively). This observation along with other lines of evidence leads us to infer the possible presence of a large, cool, diffuse medium within the proto-cluster environment evocative of a nascent intracluster medium forming in the early universe.
Context. Determining the average fraction of Lyman continuum (LyC) photons escaping high redshift galaxies is essential for understanding how reionization proceeded in the z> 6 Universe. Aims. We ...want to measure the LyC signal from a sample of sources in the Chandra Deep Field South (CDFS) and COSMOS fields for which ultra-deep VIMOS spectroscopy as well as multi-wavelength Hubble Space Telescope (HST) imaging are available. Methods. We select a sample of 46 galaxies at z ~ 4 from the VIMOS Ultra Deep Survey (VUDS) database, such that the VUDS spectra contain the LyC part, that is, the rest-frame range 880−910 Å. Taking advantage of the HST imaging, we apply a careful cleaning procedure and reject all the sources showing nearby clumps with different colours, that could potentially be lower-redshift interlopers. After this procedure, the sample is reduced to 33 galaxies. We measure the ratio between ionizing flux (LyC at 895 Å) and non-ionizing emission (at ~ 1500 Å) for all individual sources. We also produce a normalized stacked spectrum of all sources. Results. Assuming an intrinsic average Lν(1470) /Lν(895) of 3, we estimate the individual and average relative escape fraction. We do not detect ionizing radiation from any individual source, although we identify a possible LyC emitter with very high Lyα equivalent width (EW). From the stacked spectrum and assuming a mean transmissivity for the sample, we measure a relative escape fraction f escrel = 0.09 ± 0.04. We also look for correlations between the limits in the LyC flux and source properties and find a tentative correlation between LyC flux and the EW of the Lyα emission line. Conclusions. Our results imply that the LyC flux emitted by V = 25−26 star-forming galaxies at z ~ 4 is at most very modest, in agreement with previous upper limits from studies based on broad and narrow band imaging.
We present the ancillary data and basic physical measurements for the galaxies in the ALMA Large Program to Investigate C+ at Early Times (ALPINE) survey-the first large multiwavelength survey that ...aims at characterizing the gas and dust properties of 118 main-sequence galaxies at redshifts 4.4 < z < 5.9 via the measurement of emission at (64% at >3.5 ) and the surrounding far-infrared continuum in conjunction with a wealth of optical and near-infrared data. We outline in detail the spectroscopic data and selection of the galaxies as well as the ground- and space-based imaging products. In addition, we provide several basic measurements including stellar masses, star formation rates (SFR), rest-frame ultra-violet (UV) luminosities, UV continuum slopes (β), and absorption line redshifts, as well as H emission derived from Spitzer colors. We find that the ALPINE sample is representative of the 4 < z < 6 galaxy population selected by photometric methods and only slightly biased toward bluer colors (Δβ ∼ 0.2). Using as tracer of the systemic redshift (confirmed for one galaxy at z = 4.5 out of 118 for which we obtained optical λ3727 emission), we confirm redshifted Ly emission and blueshifted absorption lines similar to findings at lower redshifts. By stacking the rest-frame UV spectra in the rest frame, we find that the absorption lines in galaxies with high specific SFR are more blueshifted, which could be indicative of stronger winds and outflows.
Histologic transformation in marginal zone lymphomas Conconi, A.; Franceschetti, S.; Aprile von Hohenstaufen, K. ...
Annals of oncology,
November 2015, 2015-Nov, 2015-11-00, 20151101, Letnik:
26, Številka:
11
Journal Article
Recenzirano
Odprti dostop
Histologic transformation (HT) is a poorly understood event in patients with marginal zone lymphoma (MZL). The aim of this study was to analyze incidence and risk factors for HT in a large series of ...MZL patients.
The studied cohort included 340 MZL patients diagnosed and treated between 1995 and 2012: 157 extranodal MZLs mucosa-associated lymphoid tissue (MALT) lymphoma, 46%, 85 splenic MZLs (SMZLs, 25%) and 37 nodal MZLs (NMZLs, 11%). Sixty-one patients (18%) had bone marrow infiltration at presentation, with or without detectable involvement of peripheral blood, but without other involved sites; they were considered clonal B-cell lymphocytosis of marginal zone origin (CBL-MZ).
With a median follow-up of 4.8 years, the median overall survival and progression-free survival of the whole population were 14.5 and 5 years, respectively. HT was observed in 13 cases 3.8%, 95% confidence interval (95% CI) 2%–6.5%. Elevated lactate dehydrogenase (LDH) at diagnosis was associated with the risk of HT (P = 0.019). HT occurred in 5% of SMZLs, 4% of MALT lymphomas, 3% of NMZLs and 3% of CBL-MZ (P = 0.974). The risk of HT was 5% (95% CI 3–9%) at 5 and 10 years after diagnosis and 10% (95% CI 5%–20%) at 12 years. At the time of HT, most patients had high LDH and B symptoms. At a median follow-up of 12 months after HT, 4 of 13 patients died, all for lymphoma-related causes, with a 2-year post-transformation survival rate of 57% (95% CI 13%–86%).
In this large retrospective series, the risk of HT across all MZL types appeared lower than the one reported for follicular lymphoma.
Abstract
Fast and energetic winds are invoked by galaxy formation models as essential processes in the evolution of galaxies. These outflows can be powered either by star formation (SF) and/or active ...galactic nucleus (AGN) activity, but the relative dominance of the two mechanisms is still under debate. We use spectroscopic stacking analysis to study the properties of the low-ionization phase of the outflow in a sample of 1330 star-forming galaxies (SFGs) and 79 X-ray-detected (1042 < L
X < 1045 erg s−1) Type 2 AGN at 1.7 < z < 4.6 selected from a compilation of deep optical spectroscopic surveys, mostly zCOSMOS-Deep and VIMOS Ultra Deep Survey (VUDS). We measure mean velocity offsets of ∼− 150 km s−1 in the SFGs, while in the AGN sample the velocity is much higher (∼− 950 km s−1), suggesting that the AGN is boosting the outflow up to velocities that could not be reached only with the SF contribution. The sample of X-ray AGN has on average a lower SF rate than non-AGN SFGs of similar mass: this, combined with the enhanced outflow velocity in AGN hosts, is consistent with AGN feedback in action. We further divide our sample of AGN into two X-ray luminosity bins: we measure the same velocity offsets in both stacked spectra, at odds with results reported for the highly ionized phase in local AGN, suggesting that the two phases of the outflow may be mixed only up to relatively low velocities, while the highest velocities can be reached only by the highly ionized phase.
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