In recent decades, muon imaging has found a plethora of applications in many fields. This technique succeeds to infer the density distribution of big inaccessible structures where conventional ...techniques cannot be used. The requirements of different applications demand specific implementations of image reconstruction algorithms for either multiple scattering or absorption-transmission data analysis, as well as noise-suppression filters and muon momentum estimators. This paper presents successful results of image reconstruction techniques applied to simulated data of some representative applications. In addition to well-known reconstruction methods, a novel approach, the so-called μCT, is proposed for the inspection of spent nuclear fuel canisters. Results obtained based on both μCT and the maximum-likelihood expectation maximization reconstruction algorithms are presented.This article is part of the Theo Murphy meeting issue 'Cosmic-ray muography'.
A short description of the muon tomography demonstrator at the INFN Laboratori Nazionali di Legnaro near Padua, Italy, is given and the principal achievements owing to the data collected at that ...experimental facility are presented. In particular, the feasibility studies for several applications based on the muon-tomographic technology, within national and European projects, are discussed. The experimental problems and the procedures used to improve the performance are underlined. In addition, new activities and the related detector optimization are illustrated.This article is part of the Theo Murphy meeting issue 'Cosmic-ray muography'.
The worldwide prevalence of obstructive lung disease (OLD) is increasing, especially among people >65 years old, and nearly three in four adults with OLD have two or more comorbid conditions. This ...study describes the impact of such comorbidities on the healthcare service usage and related costs in a country with universal health coverage, basing on a large cohort of elderly patients with OLD and employing real-world data.
We carried out a retrospective cohort study on a large population of elderly (age >64 years) patients with OLD served by a Local Health Unit in northern Italy. Their comorbidities were assessed using the clinical diagnoses assigned by the Adjusted Clinical Group (ACG) system to individual patients by combining different information flows. Correlations between number of comorbidities and total annual healthcare service usage and costs were examined with Spearman's test. Regression models were applied to analyze the associations between the above-mentioned variables, adjusting for age and sex.
All types of healthcare service usage (access to emergency care; number of outpatient visits; number of hospital admissions) and pharmacy costs increased significantly with the number of comorbidities. Average total annual costs increased steadily with the number of comorbidities, ranging from € 1158.84 with no comorbidities up to € 9666.60 with 6 comorbidities or more. Poisson regression analyses showed an independent association between the number of comorbidities and the use of every type of healthcare service.
These results based on real-world data provide evidence that the burden of care for OLD patients related to their comorbidities is independent of and in addition to the burden related to OLD alone and is strongly dependent on the number of comorbidities, suggesting a holistic approach to multimorbid patients with OLD is the most sound public health strategy.
Evidence for the light-by-light scattering process, γγ→γγ, in ultraperipheral PbPb collisions at a centre-of-mass energy per nucleon pair of 5.02TeV is reported. The analysis is conducted using a ...data sample corresponding to an integrated luminosity of 390μb−1 recorded by the CMS experiment at the LHC. Light-by-light scattering processes are selected in events with two photons exclusively produced, each with transverse energy ETγ>2GeV, pseudorapidity |ηγ|<2.4, diphoton invariant mass mγγ>5GeV, diphoton transverse momentum pTγγ<1GeV, and diphoton acoplanarity below 0.01. After all selection criteria are applied, 14 events are observed, compared to expectations of 9.0±0.9(theo) events for the signal and 4.0±1.2(stat) for the background processes. The excess observed in data relative to the background-only expectation corresponds to a significance of 3.7 standard deviations, and has properties consistent with those expected for the light-by-light scattering signal. The measured fiducial light-by-light scattering cross section, σfid(γγ→γγ)=120±46(stat)±28(syst)±12(theo)nb, is consistent with the standard model prediction. The mγγ distribution is used to set new exclusion limits on the production of pseudoscalar axion-like particles, via the ▪ process, in the mass range ▪.
A search is presented for new physics in events with two low-momentum, oppositely charged leptons (electrons or muons) and missing transverse momentum in proton-proton collisions at a centre-of-mass ...energy of 13 TeV. The data collected using the CMS detector at the LHC correspond to an integrated luminosity of 35.9fb−1. The observed event yields are consistent with the expectations from the standard model. The results are interpreted in terms of pair production of charginos and neutralinos (χ˜1± and χ˜20) with nearly degenerate masses, as expected in natural supersymmetry models with light higgsinos, as well as in terms of the pair production of top squarks (t˜ ), when the lightest neutralino and the top squark have similar masses. At 95% confidence level, wino-like χ˜1±/χ˜20 masses are excluded up to 230 GeV for a mass difference of 20 GeV relative to the lightest neutralino. In the higgsino-like model, masses are excluded up to 168 GeV for the same mass difference. For t˜ pair production, top squark masses up to 450 GeV are excluded for a mass difference of 40 GeV relative to the lightest neutralino.
A search for direct production of the supersymmetric (SUSY) partners of electrons or muons is presented in final states with two opposite-charge, same-flavour leptons (electrons and muons), no jets, ...and large missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9fb−1 of proton–proton collisions at s=13TeV, collected with the CMS detector at the LHC in 2016. The search uses the MT2 variable, which generalises the transverse mass for systems with two invisible objects and provides a discrimination against standard model backgrounds containing W bosons. The observed yields are consistent with the expectations from the standard model. The search is interpreted in the context of simplified SUSY models and probes slepton masses up to approximately 290, 400, and 450 GeV, assuming right-handed only, left-handed only, and both right- and left-handed sleptons (mass degenerate selectrons and smuons), and a massless lightest supersymmetric particle. Limits are also set on selectrons and smuons separately. These limits show an improvement on the existing limits of approximately 150 GeV.
A search for a narrow Z′ gauge boson with a mass between 5 and 70 GeV resulting from an Lμ−LτU(1) local gauge symmetry is reported. Theories that predict such a particle have been proposed as an ...explanation of various experimental discrepancies, including the lack of a dark matter signal in direct-detection experiments, tension in the measurement of the anomalous magnetic moment of the muon, and reports of possible lepton flavor universality violation in B meson decays. A data sample of proton-proton collisions at a center-of-mass energy of 13 TeV is used, corresponding to an integrated luminosity of 77.3 fb−1 recorded in 2016 and 2017 by the CMS detector at the LHC. Events containing four muons with an invariant mass near the standard model Z boson mass are analyzed, and the selection is further optimized to be sensitive to the events that may contain Z→Z′μμ→4μ decays. The event yields are consistent with the standard model predictions. Upper limits of 10−8–10−7 at 95% confidence level are set on the product of branching fractions B(Z→Z′μμ)B(Z′→μμ), depending on the Z′ mass, which excludes a Z′ boson coupling strength to muons above 0.004–0.3. These are the first dedicated limits on Lμ−Lτ models at the LHC and result in a significant increase in the excluded model parameter space. The results of this search may also be used to constrain the coupling strength of any light Z′ gauge boson to muons.
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