UP - logo

Rezultati iskanja

Osnovno iskanje    Izbirno iskanje   
Iskalna
zahteva
Knjižnica

Trenutno NISTE avtorizirani za dostop do e-virov UPUK. Za polni dostop se PRIJAVITE.

48 49 50
zadetkov: 63.838
491.
  • CRISPR-based peptide librar... CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays
    Barber, Karl W.; Shrock, Ellen; Elledge, Stephen J. Molecular cell, 09/2021, Letnik: 81, Številka: 17
    Journal Article
    Recenzirano
    Odprti dostop

    CRISPR-inspired systems have been extensively developed for applications in genome editing and nucleic acid detection. Here, we introduce a CRISPR-based peptide display technology to facilitate ...
Celotno besedilo
492.
  • Programmable RNA Tracking i... Programmable RNA Tracking in Live Cells with CRISPR/Cas9
    Nelles, David A.; Fang, Mark Y.; O’Connell, Mitchell R. ... Cell, 04/2016, Letnik: 165, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    RNA-programmed genome editing using CRISPR/Cas9 from Streptococcus pyogenes has enabled rapid and accessible alteration of specific genomic loci in many organisms. A flexible means to target RNA ...
Celotno besedilo

PDF
493.
  • CYP6AE gene cluster knockou... CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides
    Wang, Huidong; Shi, Yu; Wang, Lu ... Nature communications, 11/2018, Letnik: 9, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    The cotton bollworm Helicoverpa armigera, is one of the world's major pest of agriculture, feeding on over 300 hosts in 68 plant families. Resistance cases to most insecticide classes have been ...
Celotno besedilo

PDF
494.
  • Evaluating and Enhancing Ta... Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
    Kim, Daesik; Luk, Kevin; Wolfe, Scot A ... Annual review of biochemistry, 06/2019, Letnik: 88, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Programmable nucleases and deaminases, which include zinc-finger nucleases, transcription activator-like effector nucleases, CRISPR RNA-guided nucleases, and RNA-guided base editors, are now widely ...
Celotno besedilo
495.
  • Programmable deletion, repl... Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
    Anzalone, Andrew V; Gao, Xin D; Podracky, Christopher J ... Nature biotechnology, 05/2022, Letnik: 40, Številka: 5
    Journal Article
    Recenzirano
    Odprti dostop

    The targeted deletion, replacement, integration or inversion of genomic sequences could be used to study or treat human genetic diseases, but existing methods typically require double-strand DNA ...
Celotno besedilo
496.
  • Cas9 versus Cas12a/Cpf1: St... Cas9 versus Cas12a/Cpf1: Structure–function comparisons and implications for genome editing
    Swarts, Daan C.; Jinek, Martin Wiley interdisciplinary reviews. RNA, September/October 2018, Letnik: 9, Številka: 5
    Journal Article
    Recenzirano

    Cas9 and Cas12a are multidomain CRISPR‐associated nucleases that can be programmed with a guide RNA to bind and cleave complementary DNA targets. The guide RNA sequence can be varied, making these ...
Celotno besedilo
497.
  • CRISPR–Cas9 gRNA efficiency... CRISPR–Cas9 gRNA efficiency prediction: an overview of predictive tools and the role of deep learning
    Konstantakos, Vasileios; Nentidis, Anastasios; Krithara, Anastasia ... Nucleic acids research, 04/2022, Letnik: 50, Številka: 7
    Journal Article
    Recenzirano
    Odprti dostop

    Abstract The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has become a successful and promising technology for gene-editing. To ...
Celotno besedilo
498.
  • CRISPR-Cas based antiviral ... CRISPR-Cas based antiviral strategies against HIV-1
    Wang, Gang; Zhao, Na; Berkhout, Ben ... Virus research, 01/2018, Letnik: 244
    Journal Article
    Recenzirano
    Odprti dostop

    •CRISPR-Cas9 can inhibit HIV replication.•CRISPR-Cas9 can permanently inactivate latent HIV.•CRISPR-dCas9 systems can reactivate latent HIV.•Novel CRISPR-Cas based gene therapy strategies against HIV ...
Celotno besedilo

PDF
499.
  • Contact allergy to air-expo... Contact allergy to air-exposed geraniol: clinical observations and report of 14 cases
    Hagvall, Lina; Karlberg, Ann-Therese; Bråred Christensson, Johanna Contact dermatitis, July 2012, Letnik: 67, Številka: 1
    Journal Article
    Recenzirano

    Background. The fragrance terpene geraniol forms sensitizing compounds via autoxidation and skin metabolism. Geranial and neral, the two isomers of citral, are the major haptens formed in both of ...
Celotno besedilo
500.
  • CRISPR-Cas9 Circular Permut... CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
    Oakes, Benjamin L.; Fellmann, Christof; Rishi, Harneet ... Cell, 01/2019, Letnik: 176, Številka: 1-2
    Journal Article
    Recenzirano
    Odprti dostop

    The ability to engineer natural proteins is pivotal to a future, pragmatic biology. CRISPR proteins have revolutionized genome modification, yet the CRISPR-Cas9 scaffold is not ideal for fusions or ...
Celotno besedilo

PDF

Dosegli ste najvišje možno število prikazanih rezultatov iskanja.

  • Zaradi večje učinkovitosti iskanje ponudi največ 1.000 rezultatov na poizvedbo (oz. 50 strani, če je izbrana možnost 10/stran).
  • Za nadaljnje pregledovanje rezultatov razmislite o uporabi filtrov rezultatov ali spremembi razvrstitve rezultatov.
48 49 50
zadetkov: 63.838

Nalaganje filtrov