UP - logo

Rezultati iskanja

Osnovno iskanje    Izbirno iskanje   
Iskalna
zahteva
Knjižnica

Trenutno NISTE avtorizirani za dostop do e-virov UPUK. Za polni dostop se PRIJAVITE.

1 2 3 4 5
zadetkov: 61.646
1.
  • Cancer metabolism: looking forward
    Martínez-Reyes, Inmaculada; Chandel, Navdeep S Nature reviews. Cancer, 10/2021, Letnik: 21, Številka: 10
    Journal Article
    Recenzirano

    Tumour initiation and progression requires the metabolic reprogramming of cancer cells. Cancer cells autonomously alter their flux through various metabolic pathways in order to meet the increased ...
Celotno besedilo
2.
  • Lung adenocarcinoma promotion by air pollutants
    Hill, William; Lim, Emilia L; Weeden, Clare E ... Nature (London), 04/2023, Letnik: 616, Številka: 7955
    Journal Article
    Recenzirano
    Odprti dostop

    A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an ...
Celotno besedilo
3.
  • Inflammasomes and Cancer Inflammasomes and Cancer
    Karki, Rajendra; Man, Si Ming; Kanneganti, Thirumala-Devi Cancer immunology research, 02/2017, Letnik: 5, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    Inflammation affects all stages of tumorigenesis. A key signaling pathway leading to acute and chronic inflammation is through activation of the caspase-1 inflammasome. Inflammasome complexes are ...
Celotno besedilo

PDF
4.
  • NRF2 and the Hallmarks of C... NRF2 and the Hallmarks of Cancer
    Rojo de la Vega, Montserrat; Chapman, Eli; Zhang, Donna D. Cancer cell, 07/2018, Letnik: 34, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    The transcription factor NRF2 is the master regulator of the cellular antioxidant response. Though recognized originally as a target of chemopreventive compounds that help prevent cancer and other ...
Celotno besedilo

PDF
5.
  • Tumor Dormancy and Relapse:... Tumor Dormancy and Relapse: From a Natural Byproduct of Evolution to a Disease State
    Manjili, Masoud H Cancer research (Chicago, Ill.), 05/2017, Letnik: 77, Številka: 10
    Journal Article
    Recenzirano
    Odprti dostop

    Species evolve by mutations and epigenetic changes acting on individuals in a population; tumors evolve by similar mechanisms at a cellular level in a tissue. This article reviews growing evidence ...
Celotno besedilo

PDF
6.
  • Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities
    Kerr, Emma M; Gaude, Edoardo; Turrell, Frances K ... Nature (London), 03/2016, Letnik: 531, Številka: 7592
    Journal Article
    Recenzirano
    Odprti dostop

    The RAS/MAPK (mitogen-activated protein kinase) signalling pathway is frequently deregulated in non-small-cell lung cancer, often through KRAS activating mutations. A single endogenous mutant Kras ...
Celotno besedilo

PDF
7.
  • Mitochondria and Cancer Mitochondria and Cancer
    Zong, Wei-Xing; Rabinowitz, Joshua D; White, Eileen Molecular cell, 03/2016, Letnik: 61, Številka: 5
    Journal Article
    Recenzirano
    Odprti dostop

    Decades ago, Otto Warburg observed that cancers ferment glucose in the presence of oxygen, suggesting that defects in mitochondrial respiration may be the underlying cause of cancer. We now know that ...
Celotno besedilo

PDF
8.
  • Genomic and Transcriptomic ... Genomic and Transcriptomic Analysis Reveals Incremental Disruption of Key Signaling Pathways during Melanoma Evolution
    Shain, A. Hunter; Joseph, Nancy M.; Yu, Richard ... Cancer cell, 07/2018, Letnik: 34, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    We elucidated genomic and transcriptomic changes that accompany the evolution of melanoma from pre-malignant lesions by sequencing DNA and RNA from primary melanomas and their adjacent precursors, as ...
Celotno besedilo

PDF
9.
  • Cellular Senescence: The So... Cellular Senescence: The Sought or the Unwanted?
    Sun, Yu; Coppé, Jean-Philippe; Lam, Eric W.-F. Trends in molecular medicine, October 2018, 2018-10-00, Letnik: 24, Številka: 10
    Journal Article
    Recenzirano
    Odprti dostop

    Cellular senescence is a process that results in irreversible cell-cycle arrest, and is thought to be an autonomous tumor-suppressor mechanism. During senescence, cells develop distinctive metabolic ...
Celotno besedilo
10.
  • Autophagy in malignant tran... Autophagy in malignant transformation and cancer progression
    Galluzzi, Lorenzo; Pietrocola, Federico; Bravo-San Pedro, José Manuel ... The EMBO journal, 1 April 2015, Letnik: 34, Številka: 7
    Journal Article
    Recenzirano
    Odprti dostop

    Autophagy plays a key role in the maintenance of cellular homeostasis. In healthy cells, such a homeostatic activity constitutes a robust barrier against malignant transformation. Accordingly, many ...
Celotno besedilo

PDF
1 2 3 4 5
zadetkov: 61.646

Nalaganje filtrov