Mesothelioma Risk Associated with Asbestos Production in Slovenia Vudrag, Marko (Institute of Public Health of Ljubljana, Ljubljana, Slovenia); Rihtar, Tatja (Institute of Public Health of Ljubljana, Ljubljana, Slovenia); Vegnuti, Miljana (University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia)
Arhiv za higijenu rada i toksikologiju,
03/2010, Letnik:
61, Številka:
1
Journal Article
Recenzirano
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The aim of this study was to assess malignant mesothelioma morbidity due to exposure to asbestos in a population living in districts Nova Gorica and Tolmin (49,850 people) near the asbestos ...manufacturing village Anhovo (Slovenia) and to compare it with the entire Slovene population (1,949,750 people). Crude rates per 100,000 people were calculated from the total number of mesotheliomas, and risk assessment in the studied vs. total population was based on 23 years worth of data. Time series data on mesothelioma cases were also processed as a forecast of new cases by 2010.The crude incidence of mesothelioma per 100,000 individuals for all of Slovenia was 21.4, while for the Nova Gorica district including the village Anhovo it is 170.2 and for the Tolmin district 60.9. The probability of a mesothelioma case in the studied population was 8.5 times the probability of the same diagnosis in the whole of Slovenia. Over 23 years, 28% of all mesothelioma cases in Slovenia were diagnosed in the studied population, which makes only 2.5% of the total Slovene population.The outbreak of asbestosis and mesothelioma epidemics in the studied population is associated with manufacture of asbestos products in the local factory from 1922 to 1996.
Glavni cilj raziskave je bil oceniti obolevnost za malignim mezoteliomom zaradi izpostavljenosti azbestu pri populaciji iz okolice Anhovega v dveh upravnih enotah (Nova Gorica in Tolmin), t. j. pri opazovani populaciji v primerjavi s populacijo Slovenije.Analizirani so bili statisti _ni zdravstveni podatki za opazovano populacijo (49.850 prebivalcev) v primerjavi s populacijo Slovenije (1.949.750 prebivalcev). Grobe inciden _ne stopnje na povpre _no število prebivalcev so bile izra _unane iz skupnega števila mezoteliomov, verjetnosti bolezni v opazovani populaciji in v preostanku države pa so bile izra _unane s Poissonovim verjetnostnim ra _unom na podlagi podatkov za 23 let. Časovne serije podatkov o primerih mezotelioma so bile obdelane kot napoved za število novih primerov do leta 2010.Groba incidenca mezotelioma na 100.000 prebivalcev za Slovenijo znaša 21,4, za opazovano populacijo 170,2 (obmo _je Nove Gorice vklju _no z Anhovim) in 60,9 (obmo _je Tolmina). Verjetnost za pojavnost mezotelioma v opazovani populaciji je 8,5 -krat ve _ja kot verjetnost za enako diagnozo drugje v Sloveniji. Napovedano je, da se bo v 23-letnem obdobju 28 % vseh primerov mezotelioma pojavilo v opazovani populaciji, ki predstavlja 2,5 % skupne slovenske populacije.Do izbruha epidemije azbestoze in mezotelioma v opazovani populaciji je prišlo zaradi u _inkov proizvodnje azbestnih izdelkov v lokalni tovarni med letoma 1922 in 1996. Za ljudi, ki so bili poklicno izpostavljeni azbestu, bo potrebno doživljenjsko zdravniško pregledovanje.
The aim of this study was to assess malignant mesothelioma morbidity due to exposure to asbestos in a population living in districts Nova Gorica and Tolmin (49,850 people) near the asbestos ...manufacturing village Anhovo (Slovenia) and to compare it with the entire Slovene population (1,949,750 people). Crude rates per 100,000 people were calculated from the total number of mesotheliomas, and risk assessment in the studied vs. total population was based on 23 years worth of data. Time series data on mesothelioma cases were als processed as a forecast of new cases by 2010. The crude incidence of mesothelioma per 100,000 individuals for all of Slovenia was 21.4, while for the Nova Gorica district including the village Anhovo it is 170.2 and for the Tolmin district 60.9. The probability of a mesothelioma case in the studied population was 8.5 times the probability of the same diagnosis in
the whole of Slovenia. Over 23 years, 28 % of all mesothelioma cases in Slovenia were diagnosed in the studied population, which makes only 2.5 % of the total Slovene population. The outbreak of asbestosis and mesothelioma epidemics in the studied population is associated with manufacture of asbestos products in the local factory from 1922 to 1996.
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