Abstract One of the most common palm pests is the red palm weevil, Rhynchophorus ferrugineus Olivier. Five artificial diets were evaluated to rear RPW, and to facilitate its behavioral and biological ...studies. The developmental of R. ferruginus was studied on the tested artificial diets based on primarily composed of sugarcane stem pieces (1st diet; control), sweet pumpkin (2nd diet), ground sugarcane + sweet pumpkin (3rd diet), sweet potato (4th diet) and ground sugarcane + sweet potato (5th diet) under rearing room (28 ± 1 °C and 75 ± 5 RH%) at Faculty of Agriculture in Benha district. The biological aspects, pre-oviposition, oviposition, larval & pupal durations, the longevity of male and female adults and the generation period of R. ferrugineus have all been estimated. Moreover, the impact of these artificial diets on the quantities of total proteins, carbohydrates and lipids were determined in the full-grown larvae. Obtained results showed that the insect manifested the shortest larval and pupal periods and the longest longevity for males and females when rearing of R. ferruginus took place on an artificial diet based on sweet potato as a successful and economical for mass rearing of the red palm weevil under laboratory conditions. Larvae fed on diet 4 (sweet potato) was exhibited the shortest duration (114.80 days), while 1st diet (Sugarcane stem pieces) was recorded the longest period (125.00 ± days). Similarly for pupation and both male and female longevity, the shortest periods resulted from larvae feeding on 4th diet (14.65, 49.40 and 48.0 days, respectively). Contrariwise, the longest pupal period was reported with 5th diet (15.70 days). The highest of eggs hatchability % (96.53%) resulted from the rearing nof R. ferruginus larvae on the 4th diet. Chemical analyses of the full-grown larva were indicated that the highest contents of total carbohydrates (45.57 µg/g), lipids (28.46 µg/g) and proteins (20.01µg/g) were obtained in case of larvae reared on 1st and 4th diets, respectively. Consequently, the development of R. ferruginus stages was slightly lower on both 1st and 4th artificial diets. So that, both of them were a successful and economic artificial diet for RPW development under laboratory conditions. Therefore, this study added valuable alternative ingredients to prepare more practical and economical feeding substrate for weevil rearing to help for proposal of its management and conservation in palm plantations.
Resumo Uma das pragas mais comuns das palmeiras é o gorgulho vermelho da palmeira, Rhynchophorus ferrugineus Olivier. Cinco dietas artificiais foram avaliadas para criar RPW e facilitar seus estudos comportamentais e biológicos. O desenvolvimento de R. ferruginus foi estudado nas dietas artificiais testadas baseadas principalmente em pedaços de caule de cana-de-açúcar (1ª dieta; controle), abóbora-doce (2ª dieta), cana-de-açúcar + abóbora-doce (3ª dieta), batata-doce (4ª dieta) e cana-de-açúcar moída + batata-doce (5ª dieta) em sala de criação (28 ± 1 °C e 75 ± 5 UR%) na Faculdade de Agricultura do distrito de Benha. Os aspectos biológicos, pré-oviposição, oviposição, durações de larvas e pupas, a longevidade de machos e fêmeas adultos e o período de geração de R. ferrugineus foram todos estimados. Além disso, o impacto dessas dietas artificiais nas quantidades de proteínas totais, carboidratos e lipídios foi determinado nas larvas adultas. Os resultados obtidos mostraram que o inseto manifestou os menores períodos larval e pupal e a maior longevidade para machos e fêmeas quando a criação de R. ferruginus ocorreu em uma dieta artificial à base de batata-doce como uma forma bem-sucedida e econômica para a criação massal do gorgulho vermelho da palmeira em condições de laboratório. Larvas alimentadas com a dieta 4 (batata-doce) foram as que apresentaram a menor duração (114,80 dias), enquanto a 1ª dieta (pedaços de caule de cana-de-açúcar) foi a que apresentou o maior período (125,00 ± dias). Da mesma forma para a pupação e longevidade de machos e fêmeas, os períodos mais curtos resultaram da alimentação das larvas na 4ª dieta (14,65, 49,40 e 48,0 dias, respectivamente). Ao contrário, o período pupal mais longo foi relatado com a 5ª dieta (15,70 dias). A maior porcentagem de eclodibilidade dos ovos (96,53%) resultou da criação de larvas de R. ferruginus na 4ª dieta. As análises químicas das larvas adultas indicaram que os maiores teores de carboidratos totais (45,57 µg/g), lipídios (28,46 µg/g) e proteínas (20,01µg/g) foram obtidos no caso de larvas criadas na 1ª e 4ª dietas, respectivamente. Consequentemente, o desenvolvimento dos estádios de R. ferruginus foi ligeiramente menor tanto na 1ª quanto na 4ª dieta artificial. Assim, ambas foram dietas artificiais bem-sucedida e econômica para o desenvolvimento de RPW em condições de laboratório. Portanto, este estudo adicionou ingredientes alternativos valiosos para preparar substrato alimentar mais prático e econômico para a criação do gorgulho para auxiliar na proposta de seu manejo e conservação em plantações de palmeiras.
Abstract Zatrephina lineata (Coleoptera: Chrysomelidae) is a phytophagous insect, mainly of plants of the genera Ipomoea and Mikania. The objective was to study the development, survival and to ...describe the life stages of Z. lineata fed on leaves of Ipomoea pes-caprae. Biological observations were made daily with the aid of a stereoscopic microscope and the instars of this insect identified by the exuvia left between one moulting and the next. The duration of development and survival of the egg, larva and pupa stages and the first, second, third, fourth and fifth instars and of the nymph stage of Z. lineata differed, but not between sexes of this insect. The duration of development of Z. lineata was longer in the larval stage and in the fifth instar, and its survival greater in the egg and pupa stages and in the first and fifth instars. Zatrephina lineata eggs, cream-colored, are ellipsoid and deposited in groups on the adaxial surface of older I. pes-caprae leaves. The larvae of this insect go through five instars, with the first three being gregarious with chemo-behavioral defenses. The exarated pupae of Z. lineata, light yellow in color and with an oval shape flattened dorsoventrally, attach to the abaxial surface of the I. pes-caprae leaves. The shape of adults of this insect is oval, straw yellow in color with lighter longitudinal stripes and females are slightly larger than males.
Resumo Zatrephina lineata (Fabricius, 1787) (Coleoptera: Chrysomelidae) é um inseto fitófago, principalmente de plantas dos gêneros Ipomoea e Mikania. O objetivo foi estudar o desenvolvimento, a sobrevivência e descrever as fases de vida de Z. lineata alimentada com folhas de Ipomoea pes-caprae. Observações biológicas foram feitas diariamente com auxílio de microscópio estereoscópico e os ínstares desse inseto identificados pela exúvia deixada entre uma muda e outra. A duração do desenvolvimento e sobrevivência dos estágios de ovo, larva e pupa e dos primeiro, segundo, terceiro, quarto e quinto ínstares e do periodo ninfal de Z. lineata diferiu, mas não entre os sexos deste inseto. A duração do desenvolvimento de Z. lineata foi maior na fase larval e no quinto ínstar, e sua sobrevivência maior nas fases de ovo e pupa e no primeiro e quinto ínstares. Os ovos de Z. lineata, de cor creme, são elipsoides e depositados em grupos na superfície adaxial das folhas mais velhas de I. pes-caprae. As larvas desse inseto passam por cinco ínstares, sendo os três primeiros gregários com defesas quimio-comportamentais. As pupas exaradas de Z. lineata, de cor amarelo claro e formato oval achatado dorsoventralmente, fixam-se na superfície abaxial das folhas de I. pes-caprae. O formato dos adultos deste inseto é oval, de cor amarelo palha com listras longitudinais mais claras e as fêmeas são ligeiramente maiores que os machos.
The present study included to know about the effectiveness of steep chickpea Cicer arietinum L. seeds with ethanolic and aqueous extracts of the Oleander Nerium oleander, Basil Ocimum basilicum, ...Chinaberry Melia azedarach, and Natgrass Cyperus rotundus leaves with four concentration (0.5, 1.0, 2.5, 5.0) % on some biological sides of the cowpea beetle Callosobruchus maculatus (Fab.). The present study showed the superiority of leaves extracts of Oleander and Chinaberry as compared with leaves extracts of Basil and Natgrass, as well as the superiority of aqueous extracts as compared with ethanolic extracts of the present study plant's leaves on some biological sides of the cowpea beetle C. maculatus (Fab.). Also, the present study showed that the least number of laid eggs was recorded at a concentration of 1.0% of the ethanolic extract of the chinaberry with several 31.5 eggs, the least percentage of hatched eggs was recorded in the aqueous extract of chinaberry at a concentration of 5.0% with a percentage of 64.8%, the highest larval stage period was recorded at a concentration of 5.0% of the ethanolic extract of the chinaberry with a period of 19.8 days. Total mortality (100%) in the larval stage was achieved with a concentration of 5.0% of the aqueous extracts of the Oleander and Chinaberry. The highest pupal stage period was recorded at 5.0% of the ethanolic extract of the chinaberry at 14.8 days. The highest mortality in the pupal stage was recorded at a concentration of 2.5 % of the aqueous extract of the chinaberry with a percentage of 23.0%. The least number of emerged adults in the first generation and least percentage of productivity were recorded at a concentration of 5.0 % of the aqueous extracts of the Oleander and Chinaberry, with several 0.0 adults and a percentage of 0.0%, respectively.The study also showed that the germination percentage of Chickpea seeds was not significantly affected when it was treated with different concentrations of ethanolic and aqueous extracts of the present study plants' leaves.
For the past 50 years Marine sponges have been considered as a gold mine. Marine sponges are secondary metabolites and considered as a drug treasure house. Most of the discoveries and studies have ...been conducted on sponge’s derived compounds to study its pharmacological properties. Marine sponges belong to the family of phylum Porifera (Metazoa), which is the only one best source of marine natural products. Sponges are multicellular and their bodies are full of pores and channels which allow water to circulate through them. Genus Stelletta are well known marine sponges which are a rich source of natural products including lipids, terpenoids, peptides, alkaloids and steroids. Due to its biological activities and novel structure various chemists discover new drugs to cure from various diseases. These have antifungal, antimalarial, antibacterial, antiviral, antitumor, immunosuppressive, and cardiovascular activity
The tumor microenvironment (TME) play critical roles in tumor survival, progression, and metastasis and can be considered potential targets for molecular imaging of cancer. The targeting agents for ...imaging of TME components (
e.g.
, fibroblasts, mesenchymal stromal cells, immune cells, extracellular matrix, blood vessels) provide a promising strategy to target these biomarkers for the early diagnosis of cancers. Moreover, various cancer types have similar tumor immune microenvironment (TIME) features that targeting those biomarkers and offer clinically translatable molecular imaging of cancers. In this review, we categorize and summarize the components in TME which have been targeted for molecular imaging. Moreover, this review updated the recent progress in targeted imaging of TIME biological molecules by various modalities for the early detection of cancer.
Graphical Abstract
Coleopterans within the family Coccinellidae play an important role in the biological control of
MEAM1 Gennadius (Hemiptera: Aleyrodidae), a worldwide pest. Here we report an initial assessment of ...the predatory capacity and biological aspects of a South American coccinellid,
Gordon (Coleoptera: Coccinellidae) to
immature stages under laboratory conditions. Within the 24 h after release,
adults were increasingly more attracted to and consumed six times more
fourth instar nymphs than the remaining immature stages. Similarly,
larvae also had a greater consumption of
fourth instar nymphs within 24 h after release. Within 10 days after larvae release, there were no significant differences in preference between the nymphal stages. Both
adults and larvae presented a better biological performance when fed with
fourth instar nymphs. The larval developmental time and pupal survival for
was optimal when fed fourth instar nymphs. These findings highlight the potential for implementing
in integrated pest management (IPM) programs for
and warrant further evaluation under greenhouse and semi-field conditions.
A novel series of anticipated biologically active heterocyclic compounds, such as pyrazole, thiazole, pyridine, acrylamide, thiophene, triazolo1,5-
pyrimidine, imidazolidine, aminopyrazole, ...pyrazolo5,1-
1,2,4triazine, triazolo4,3-
pyrimidine, benzo4,5imidazo1,2-
pyrimidine, pyrido2',3':3,4pyrazolo5,1-
1,2,4triazine, isoxazole, benzo4,5imidazo2,1-
1,2,4triazine, pyrimidine, pyrido2',3':3,4pyrazolo1,5-
pyrimidine, pyrano2,3-
pyrimidine, and chromene derivatives, incorporating a sulfonamide-bearing thiazole moiety suitable to utilize as insecticidal agents were synthesized via a versatile, readily accessible cyanoacetanilide, 2-cyano-
-(4-(
-(thiazol-2-yl)sulfamoyl)phenyl)acetamide (
).The structures of the newly synthesized compounds were elucidated by IR, MS,
H NMR,
C NMR, distortionless enhancement by polarization transfer (DEPT),
H-
H correlation spectroscopy (COSY), heteronuclear multiple bond correlation (HMBC), and heteronuclear single quantum coherence (HSQC) spectral analysis. Toxicological and biochemical parameters and biological aspects of the demonstrated compounds of the synthesized products against the cotton leafworm,
, under laboratory conditions were also investigated. Regarding the determined LC
and LC
values, sulfonamides bearing a thiazole moiety,
,
,
, and
, showed the most potent toxic effects with LC
values of 49.04, 62.66, 78.62, and 94.90 ppm, respectively, and toxicity index of 100%, 78.26%, 62.38%, and 51.68%, respectively.
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