Two cases are reported of cold-induced dysaesthesia occurring during an attack of acute idiopathic polyneuritis. Two similar cases found in the literature are reviewed. It is suggested that the ...dysaesthesia may be a localized symptom of cold sensitivity, with an initiating trigger in common with acute idiopathic polyneuritis.
A suction blister device with a sensitive thermometer and with a temperature regulator was constructed. Utilizing this device, it was demonstrated that the cold challenge induces an increase in the ...skin temperature in cold urticaria patients during the cold challenge and a simultaneous release of histamine into the suction blisters. The skin temperature increases faster after the cold challenge period in cold urticaria patients than in normal control persons. This could be explained by vasodilatation and increased circulation in the skin, following the release of histamine in the cold urticaria reaction.
This is a clinical description of an unusual arthropathy in 2 members of a family with familial cold urticaria. Relevant investigations, X-ray illustrations and the family pedigree are presented. The ...nature of the arthropathy and its possible relationship to other arthropathies is discussed.
A patient with lymphosarcoma and cold urticaria showed evidence of complement activation by the classical pathway with low levels of the early complement components, normal levels of late acting ...components, normal functioning of the alternate pathway and reduction of the C1-inhibitor level. The serum contained an IgG1 monoclonal cryoglobulin responsible for the complement activation. In vitro tests demonstrated a high capacity of the serum to activate C1.
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