Wilfred Bion’s theories of dreaming, of the analytic situation, of reality and everyday life, and even of the contact between the body and the mind offer very different, and highly fruitful, ...perspectives on lived experience. Yet very little of his work has entered the field of visual culture, especially film and media studies. Kelli Fuery offers an engaging overview of Bion’s most significant contribution to psychoanalysis- his theory of thinking- and demonstrates its relevance for why we watch moving images.
Bion’s theory of thinking is presented as an alternative model for the examination of how we experience moving images and how they work as tools which we use to help us ‘think’ emotional experience. ‘Being Embedded’ is a term used to identify and acknowledge the link between thinking and emotional experience within the lived reception of cinema. It is a concept that everyone can speak to as already knowing, already having felt it - being embedded is at the core of lived and thinking experience. This book offers a return to psychoanalytic theory within moving image studies, contributing to the recent works that have explored object relations psychoanalysis within visual culture (specifically the writings of Klein and Winnicott), but differs in its reference and examination of previously overlooked, but highly pivotal, thinkers such as Bion, Bollas and Ogden. A theorization of thinking as an affective structure within moving image experience provides a fresh avenue for psychoanalytic theory within visual culture.
Wilfred Bion, Thinking, and Emotional Experience with Moving Images will appeal to psychoanalysts and psychoanalytic psychotherapists, as well as scholars and students of film and media studies, cultural studies and cultural sociology and anthropology, visual culture, media theory, philosophy, and psychosocial studies.
Even though the long-term variability of glucose homeostasis has emerged as a risk factor for adverse outcomes in diabetes, there exists no universal consensus on its definition and assessment, but ...the determination of quarterly HbA1c fluctuations would be an appropriate metric. From the analysis of retrospective studies conducted in persons with type 2 diabetes, the risk for adverse outcomes appears to become significantly increased when the coefficient of variation for HbA1c (%CV for HbA1c) is above 5.0%. However, should the number of HbA1c readings be greater than four for completing a clinically relevant assessment, the follow-up period would be longer than one year. Such a delay is not clinically acceptable for rapid clinical decisions. To conciliate the scientific relevance and practical approaches with minimal number of HbA1c measurements, we assessed the HbA1c variability from two successive HbA1c readings. For perspective in care the 5.0% threshold of the %CV for HbA1c was converted into lower and upper limits of visit-to-visit differences in absolute HbA1c levels. These HbA1c dependent limits (± 0.X% i.e., X/10% for an HbA1c level of X%) easily permit to decipher HbA1c stability and lability in diabetes across the spectrum of HbA1c levels and further to adjust the treatment.
The Definition of Reuse van de Sandt, Stephanie; Dallmeier-Tiessen, Sünje; Lavasa, Artemis ...
Data science journal,
06/2019, Letnik:
18, Številka:
4/5
Journal Article
Recenzirano
Odprti dostop
The ability to reuse research data is now considered a key benefit for the wider research community. Researchers of all disciplines are confronted with the pressure to share their research data so ...that it can be reused. The demand for data use and reuse has implications on how we document, publish and share research in the first place, and, perhaps most importantly, it affects how we measure the impact of research, which is commonly a measurement of its use and reuse. It is surprising that research communities, policy makers, etc. have not clearly defined what use and reuse is yet. We postulate that a clear definition of use and reuse is needed to establish better metrics for a comprehensive scholarly record of individuals, institutions, organizations, etc. Hence, this article presents a first definition of reuse of research data. Characteristics of reuse are identified by examining the etymology of the term and the analysis of the current discourse, leading to a range of reuse scenarios that show the complexity of today's research landscape, which has been moving towards a data-driven approach. The analysis underlines that there is no reason to distinguish use and reuse. We discuss what that means for possible new metrics that attempt to cover Open Science practices more comprehensively. We hope that the resulting definition will enable a better and more refined strategy for Open Science. Keywords: reuse, research data, open science, definition, characteristics
Bernard M. Bass (1990), John P. Kotter (1988), and Joseph C. Rost (1993) defined leadership in different meanings. Among the three definitions, Rost’s definition can be as a practical application as ...well as providing guiding principles for lecturers’ leadership development. Leadership is not a person and it is different from management. Leadership is an influence relationship among leaders and followers who intend real changes that reflect their mutual purposes. Four essential elements that must be present if leadership exists are: (1) the relationship is based on influence, (2) leaders and followers are people in this relationship, (3) leaders and followers intend real changes, and (4) leaders and followers develop mutual purposes.
High-definition intravascular ultrasound (HD-IVUS) utilizing more than 80 MHz frequency to assess atherosclerotic plaque, can theoretically achieve an axial resolution of less than <inline-formula> ...<tex-math notation="LaTeX">20~\mu \text{m} </tex-math></inline-formula>. However, the blood is a high-attenuation source at high frequency, which would affect the imaging quality. There has been no research evaluating the blood-induced influence on HD-IVUS imaging. And whether a temporary removal of blood is needed for HD-IVUS is unknown. In this study, an ultrahigh-frequency (100 MHz) ultrasound transducer was developed to evaluate the blood-induced attenuation for HD-IVUS imaging. A series of tungsten-wire phantom images in saline and blood at varying hematocrits were obtained. The images showed that blood did influence the ultrahigh-frequency imaging quality greatly. The signal-to-noise ratio (SNR) decrease by 71.7% in porcine whole blood compared to that in saline at the same depth of 2.3 mm. Moreover, the potential flushing schemes for HD-IVUS were studied in varying hematocrits. Three flushing agents commonly used in intravascular optical coherence tomography (IV-OCT) were investigated, including iohexol, mannitol, and dextran 5% and saline as the control group. The attenuation of blood in varying hematocrits/flushing agents was measured from 90 to 110 MHz. The result indicated dextran 5% was a suitable flushing agent for HD-IVUS due to its less signal attenuation compared to others.
The term 'heavy metals' is commonly used in the environmental literature to refer to metals and metalloids associated with environmental pollution, toxicity and adverse effects on biota. The term has ...been diversely defined, mostly in terms of density, relative atomic mass and atomic number. This diversity of definitions has raised questions about the nomenclature of these elements. The inclusion of the metalloid As and the nonmetal Se with heavy metals is also an important issue. Some people have called the term as meaningless, imprecise and poorly defined and have suggested abandoning the use of the term. The term itself may not be problematic but the careless and inconsistent use of terminology has led to a confusion about the meaning of the term. The use of the term may be continued but it should be defined in a more comprehensive and scientific way. Here, a more comprehensive definition of the term 'heavy metals' is suggested as 'naturally occurring metals having atomic number (Z) greater than 20 and an elemental density greater than 5 g cm
−3
.' A screening of the Periodic Table according to this definition yields 51 elements to be called 'heavy metals.' As and Se are excluded from heavy metals.
In this article we study some spectral properties of the linear operator LΩ+a defined on the space C(Ω¯) by:LΩφ+aφ:=∫ΩK(x,y)φ(y)dy+a(x)φ(x) where Ω⊂RN is a domain, possibly unbounded, a is a ...continuous bounded function and K is a continuous, non-negative kernel satisfying an integrability condition.
We focus our analysis on the properties of the generalised principal eigenvalue λp(LΩ+a) defined byλp(LΩ+a):=sup{λ∈R|∃φ∈C(Ω¯),φ>0,such that LΩφ+aφ+λφ≤0 in Ω}.
We establish some new properties of this generalised principal eigenvalue λp. Namely, we prove the equivalence of different definitions of the principal eigenvalue. We also study the behaviour of λp(LΩ+a) with respect to some scaling of K.
For kernels K of the type, K(x,y)=J(x−y) with J a compactly supported probability density, we also establish some asymptotic properties of λp(Lσ,m,Ω−1σm+a) where Lσ,m,Ω is defined by Lσ,2,Ωφ:=1σ2+N∫ΩJ(x−yσ)φ(y)dy. In particular, we prove thatlimσ→0λp(Lσ,2,Ω−1σ2+a)=λ1(D2(J)2NΔ+a), where D2(J):=∫RNJ(z)|z|2dz and λ1 denotes the Dirichlet principal eigenvalue of the elliptic operator. In addition, we obtain some convergence results for the corresponding eigenfunction φp,σ.
Alternative splicing (AS) is a crucial regulatory mechanism in eukaryotes, which acts by greatly increasing transcriptome diversity. The extent and complexity of AS has been revealed in model plants ...using high-throughput next-generation sequencing. However, this technique is less effective in accurately identifying transcript isoforms in polyploid species because of the high sequence similarity between coexisting subgenomes.
Here we characterize AS in the polyploid species cotton. Using Pacific Biosciences single-molecule long-read isoform sequencing (Iso-Seq), we developed an integrated pipeline for Iso-Seq transcriptome data analysis (https://github.com/Nextomics/pipeline-for-isoseq).
We identified 176 849 full-length transcript isoforms from 44 968 gene models and updated gene annotation. These data led us to identify 15 102 fibre-specific AS events and estimate that c. 51.4% of homoeologous genes produce divergent isoforms in each subgenome. We reveal that AS allows differential regulation of the same gene by miRNAs at the isoform level. We also show that nucleosome occupancy and DNA methylation play a role in defining exons at the chromatin level.
This study provides new insights into the complexity and regulation of AS, and will enhance our understanding of AS in polyploid species. Our methodology for Iso-Seq data analysis will be a useful reference for the study of AS in other species.
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•Only unavoidable inedible processing food waste used for high-value products.•Main products included are acids, bioplastics, colorants, enzymes and other.•149 examples with ...productivity/yield data, including 75 fermentation examples.•Stepwise guiding criteria for using food waste in circular economy context.•Uncovered definitional limitations of food waste and need for holistic assessment.
Processing of food is linked to unavoidable and inedible food waste that, despite efforts to minimize waste, will persevere. It nevertheless represents a stable feedstock for the future bioeconomy value chains and products. This study presents a systematic review of 149 examples from the scientific literature using inedible, unavoidable food residues and wastes for the production of value-added bio-based compounds that could substitute synthetic chemicals production. The main high-value products investigated are organic acids, bioplastics, colorants, enzymes and other platform chemicals. We found 44 examples of acid production with high variability in output (from 43 to 640 g kg−1waste), 9 examples of bioplastics (from 0.28 to 49 g L−1), 26 examples related to colorants (from 0.04 to more than 400 mg per 100 g), 22 cases of enzyme production (from 6000 Ug−1), 4 examples of protein (23.6 to 38.5 %wt. DM) and 44 cases of other high-value molecules such as pectin and single cell oils. Our findings highlight fermentation as a key technology for the valorization of the studied feedstock, with 76 examples out of the 149 reviewed. The review process also uncovered important limitations related to the lack of standardized food waste definitions, a barrier that is discussed and for which solutions are proposed. At the light of our findings, we further proposed guiding criteria towards the sustainable development of future biorefineries based on food waste. This work touches upon several Sustainable Development Goals, in particular goals 8.2, 9.5, and 12.3.
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