To examine the association of strength training (ST) activity with impaired glucose metabolism (IGM) in Australian adults.
On the basis of an oral glucose tolerance test, IGM (which includes impaired ...fasting glucose, impaired glucose tolerance, or newly diagnosed type 2 diabetes), was assessed in 5831 adults (mean age = 56.0 +/- 12.7 yr) without clinically diagnosed diabetes who participated in the 2004–2005 Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Meeting the current ST guideline was based on reporting ST at least two times per week (frequency) or > or = 40 min x wk(-1) in total (duration). Multiple logistic regression analyses examined associations of self-reported ST frequency and duration with IGM.
After adjustment for known confounding factors and total moderate- to vigorous-intensity leisure time exercise, the odds ratio (OR) of IGM was 0.73 (95% confidence interval CI = 0.59–0.91, P < or = 0.005) in those who met the ST frequency guideline (two or more times per week) and 0.69 (95% CI = 0.55–0.87, P < or = 0.01) in those who met the ST duration guideline (> or =40 min x wk(-1)). Those who achieved both the recommended frequency and duration of ST had 24% lower odds of IGM. There was also evidence that a moderate frequency (once a week) and duration (10–39 min x wk(-1)) of ST reduced the odds of IGM (OR frequency = 0.53, 95% CI = 0.51–0.81, P e 0.01; OR duration = 0.72, 95% CI = 0.52–1.00, P < or = 0.05).
These findings support the importance of including ST activity, at a frequency of at least once per week, within exercise management recommendations for the maintenance of favorable metabolic health, particularly as it may contribute to reducing the risk of developing type 2 diabetes mellitus.
Abstract
Background
Physical activity has been associated with reduced risk of seven types of cancer. It remains unclear, however, whether muscle-strengthening activities also reduce cancer incidence ...and mortality.
Methods
PubMed, Embase, Web of Science and Scopus were searched from inception to March 2020. Summary hazard ratio (HR) and 95% confidence intervals (CI) were estimated using random-effects models.
Results
Twelve studies (11 cohorts; 1 case-control), 6 to 25 years of follow-up, including 1,297,620 participants, 32,196 cases and 31,939 deaths, met inclusion criteria. Muscle-strengthening activities were associated with a 26% lower incidence of kidney cancer (HR for high vs low levels of muscle-strengthening activities: 0.74; 95% CI 0.56 to 0.98;
I
2
0%; 2 studies), but not with incidence of other 12 types of cancer. Muscle-strengthening activities were associated with lower total cancer mortality: HRs for high vs low levels of muscle-strengthening activities was 0.87 (95% CI 0.73 to 1.02;
I
2
58%; 6 studies); and HR for ≥2 times/week vs < 2 times/week of muscle-strengthening activities was 0.81 (95% CI 0.74 to 0.87;
I
2
0%; 4 studies). Regarding the weekly duration of muscle-strengthening activities, HR for total cancer mortality were 0.91 (95% CI 0.82 to 1.01;
I
2
0%; 2 studies) for 1–59 min/week and 0.98 (95% CI 0.89 to 1.07;
I
2
0%) for ≥60 min/week vs none. Combined muscle-strengthening and aerobic activities (vs none) were associated with a 28% lower total cancer mortality (HR 0.72; 95% CI 0.53 to 0.98;
I
2
85%; 3 studies).
Conclusions
Muscle-strengthening activities were associated with reduced incidence of kidney cancer and total cancer mortality. Combined muscle-strengthening and aerobic activities may provide a greater reduction in total cancer mortality.
Summary
Objective
Emerging research demonstrates that aerobic‐based physical activity is favourably associated with episodic memory function. Despite resistance exercises being associated with a ...multitude of health outcomes, independent of aerobic physical activity, less research has examined the effects of resistance exercise on episodic memory function. The purpose of this study was to conduct a systematic review to examine the extent to which resistance exercise may be associated with episodic memory function.
Methods
Computerized searches were performed in PubMed, PsychInfo and Sports Discuss. Studies were included if they employed an experimental, cross‐sectional or prospective study design, and included acute or chronic resistance exercise as the independent variable, with episodic memory function as the outcome variable.
Results
Eight experimental (one acute and seven chronic training studies) studies met the study inclusionary criteria. Seven of these studies were published in the last 5 years, highlighting the infancy of this line of research. Only three of the eight evaluated studies provided evidence of a positive effect of resistance exercise on memory function; within each of these three studies, there was also some indication of null (or unfavourable) effects.
Conclusion
The findings of this systematic review do not provide compelling evidence for a beneficial effect of acute or chronic resistance exercise on episodic memory function. Additional research in this under‐investigated field is warranted.
Non-communicable diseases have become a major threat to public health, with cardiovascular diseases (CVDs) and cancer being the top two causes of death each year.
Our objective is to evaluate the ...balanced association between the effect of red and processed meat intake on the risk of death and the effect of physical activity on the risk of mortality, where the risk of death includes all causes, CVDs, and cancers.
We searched electronic databases, including PubMed, ISI Web of Science, Embase, and the Cochrane Library, for prospective studies reporting risk estimates for the association between the intake of red and processed meat, walking, and muscle-strengthening activity (MSA) and the risk of mortality from all causes, CVDs, and cancer. We extracted fully adjusted effect estimates from original studies and performed a summary analysis using the fixed and random-effect models.
A conventional meta-analysis showed that red meat and processed meat were positively associated with the risk of mortality, and daily steps and MSA were negatively associated with the risk of death. Further analysis of the dose-response relationship showed that a risk reduction (20%) from 39.5 min/week of MSA or 4100 steps/d was equivalent to an increased risk of all-cause mortality from a daily intake of 103.4 g/d of red meat or 50 g/d of processed meat. The risk was further decreased as the number of steps per day increased, but the risk reversed when the MSA exceeded the threshold (39.5 min/week).
Adherence to physical activity is an effective way to reduce the risk of mortality due to meat intake. However, the total intake of red meat and processed meat should be controlled, especially the latter. Walking is recommended as the main daily physical activity of choice, while MSAs are preferred when time is limited, but it should be noted that longer MSAs do not provide additional benefits.
Recently, new physical activity (PA) guidelines were adopted in the Netherlands consisting of two components: (1) addressing duration of moderate and vigorous PA, (2) bone and muscle strengthening ...activities. The aim of this study is to retrospectively assess the long-term trend in fulfilling the criteria of the new PA guidelines and to gain insight into which activities contribute to changes over time. Data were available for 2001-2018 of a nationally representative sample of approximately 7000 Dutch citizens aged 12 years and over using the Short Questionnaire to Assess Health-enhancing physical activity (SQUASH). Multiple logistic regression analysis was performed by age, sex, and level of education. Overall, a positive trend was found from 39.9% adherence in 2001 to 46.0% in 2018. Adherence levels among adolescents decreased and increased among adults and seniors. Intermediate and higher educated groups showed positive trends over time whereas a stable trend was observed among lower educated. Activities contributing most to changes over time were sports, leisure time walking, and strenuous occupational activities. In the period 2001-2018, though an increasing trend was found, less than half of the population was sufficiently active. Special effort is necessary to reach adolescents, seniors, and lower educated groups in PA promotion programs.
Healthy Diet and physical activity may play important roles in the maintenance of muscle health during aging. The aim of the present study was to explore the impact of adherence to healthy dietary ...patterns on sarcopenia risk in a sample of physically active older men and women, while considering adherence to guidelines on muscle strengthening activities (MSA) and protein intake. Based on a sample of 191 physically active men and women (65–70 years), dietary intake was assessed using a 90-items food-frequency-questionnaire (FFQ) and Healthy Diet Score (HDS) was calculated. Physical activity was assessed by accelerometry and self-report. A sarcopenia risk score (SRS) was derived based on three indicators of muscle health: muscle mass was assessed using bioelectrical impedance and handgrip strength and 5 times sit-to-stand (5-STS) were determined by standardized procedures. Analysis of covariance (ANCOVA) was used to examine differences in SRS and its components across sex-specific tertiles of HDS, with adjustments for covariates including total energy intake, protein intake and MSA. A significant main effect (p < 0.05) of HDS on SRS was observed, where those belonging to the highest HDS tertile had lower SRS compared to those in the lowest tertile. A corresponding significant effect was observed for 5-STS performance, with better performance in those with the highest HDS adherence compared to those with the lowest. The present study supports guidelines emphasizing diet quality beyond amounts of macro- and micronutrients in the prevention of age-related deterioration of muscle health. Importantly, the benefits from healthy dietary patterns are evident in older adults who already adhere to guidelines for health-enhancing physical activity.
•This study showed low levels of muscle-strengthening activities among pre-, peri- and post-menopausal women.•Knowledge and negative attitudes were important issues that influenced women’s intention ...to perform muscle-strengthening activities.•Self-efficacy and affective attitudes were identified as significant predictors of intention to perform muscle-strengthening activities.•Findings were independent of menopausal status.
Although physical activity guidelines recommend muscle-strengthening activities (MSA), public health initiatives tend to focus on increasing aerobic activity and fail to mention MSA. This study sought to identify the issues influencing pre-, peri- and post-menopausal women’s intentions to perform MSA with a view to informing future interventions for these populations. Mixed methods guided by the Theory of Planned Behaviour (TPB) were used to explore factors that influence women’s intentions to perform MSA. In stage one, 34 women participated in either a focus group or interview. Discussions were transcribed verbatim and analysed based on menopausal status using a deductive approach. In stage two, 186 women (M = 47 years, SD = 9) completed a questionnaire to assess participant demographics, levels of MSA, affective and instrumental attitudes, injunctive and descriptive norms, self-efficacy and perceived behavioural control. Quantitative data were analysed using descriptive statistics, bivariate correlations, regression analyses and analysis of variances. Behavioural beliefs were: improved muscular health; psychological benefits; improved body shape. Normative beliefs were: health professionals; family members; work colleagues. Control beliefs were: equipment; motivation; time constraints; knowledge; physical capability; fear of judgement. However, these beliefs were not well established. Self-efficacy was the strongest predictor of intentions (spc2 = 0.11) followed by affective attitudes (spc2 = 0.09), with no significant differences on TPB variables between groups. If rising rates of musculoskeletal conditions in women are to be prevented, there is an urgent need to increase women’s knowledge of recommended levels of muscle strengthening, with a view to promoting positive attitudes and enhancing women’s sense of self-efficacy across all menopausal phases.
Purpose.
Physical activity (PA) has previously been demonstrated to be inversely related with multimorbidity (having more than one chronic disease); however, it is unknown whether dual participation ...in both PA and muscle-strengthening activities (MSA) may further reduce the odds of being multimorbid. Therefore, the purpose of our study was to determine the association between multimorbidity and individuals meeting recommended guidelines for both PA and MSA.
Design.
Nonexperimental.
Setting.
The 2003–2006 National Health and Nutritional Examination Survey.
Subjects.
Four thousand five hundred eighty-seven adults aged ≥20 years.
Measures.
Accelerometry-measured PA, self-reported MSA, and multimorbidity.
Analysis.
Data were analyzed using multivariable linear and logistic regression.
Results.
The odds (95% confidence interval) of being multimorbid for those only meeting MSA guidelines, only meeting PA guidelines, and meeting both PA and MSA guidelines (vs. not meeting either), respectively, were .69 (.48, .98; p = .04), .55 (.44, .70; p < .01), and .38 (.27, .53; p < .01).
Conclusion.
Our findings demonstrate that individuals meeting recommended guidelines for both MSA and PA were less likely to be multimorbid than individuals participating in one or none of these exercise modalities. Determining effective ways to initiate and maintain concurrent adoption of MSA and PA is needed to provide a cost-effective behavioral alternative for reducing the prevalence of multimorbidity.
Systemic inflammation is believed to contribute to declining muscle health during aging. The present study aims to examine associations between indicators of muscle health and pro- and ...anti-inflammatory biomarkers in older men and women, while also considering the impacts of physical activity and protein intake. An assessment of skeletal muscle index (SMI) by bioelectrical impedance analysis, handgrip strength, and 5-sit-to-stand time, using standardized procedures, was conducted in a population of older men (n = 90) and women (n = 148) aged 65–70 years. The inflammatory biomarkers C-reactive protein (CRP), fibrinogen, interleukin (IL)-6, IL-10, IL-18, tumor necrosis factor (TNF)-α, monocyte chemoattractant protein-1, and macrophage inflammatory protein-1α were assessed in blood samples. Data were analyzed and stratified according to biological sex using multiple linear regression models. In older women, SMI was inversely associated with the pro-inflammatory markers CRP (β = −0.372; p < 0.05), fibrinogen (β = −0.376; p < 0.05), and IL-6 (β = −0.369; p < 0.05). Importantly, these associations were independent of abdominal adiposity (waist circumference), protein intake, physical activity level, as well as any adherence to muscle strengthening guidelines (≥2 sessions/week). In contrast, no corresponding associations were observed in men. In conclusion, our findings indicate the detrimental influence of a pro-inflammatory environment on muscle health regardless of important lifestyle-related factors in older women. However, the lack of such associations in older men highlights the importance of considering biological sex when examining the complex interaction between the systemic inflammatory environment and muscle health.
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