The Zika outbreak, spread by the Aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective way. Here we combine Hi-C data with ...existing draft assemblies to generate chromosome-length scaffolds. We validate this method by assembling a human genome, de novo, from short reads alone (67× coverage). We then combine our method with draft sequences to create genome assemblies of the mosquito disease vectors Ae. aegypti and Culex quinquefasciatus, each consisting of three scaffolds corresponding to the three chromosomes in each species. These assemblies indicate that almost all genomic rearrangements among these species occur within, rather than between, chromosome arms. The genome assembly procedure we describe is fast, inexpensive, and accurate, and can be applied to many species.
Traditional educational giants and natural language processing companies have launched several artificial intelligence (AI)‐enabled digital learning applications to facilitate language learning. One ...typical application of AI in digital language education is the automatic scoring application that provides feedback on pronunciation repeat outcomes. This research is motivated by the usage of automatic scoring‐empowered digital learning tools by language learners, and set out to uncover the influencing mechanisms of AI‐enabled automatic scoring application affordances on learners’ continuous learning intention. Specifically, based on affordance theory, we found several automatic scoring application affordances through in‐depth interviews. Considering the current lack of investigations on the mechanisms underlying automatic scoring application and its implications for learners’ learning behaviors, we built a model to examine the role of automatic scoring application affordances on cognitive/emotional engagement and following continuous learning intention. We further examined the moderation role of in‐job learners and student learners on the above relationships. The model was tested using a survey of 260 Chinese foreign language learners who used AI‐empowered learning tools to facilitate their language learning practices. This study explores why learners continuously use AI‐enabled automatic scoring applications by identifying the affordances that differentiate it from traditional educational technologies. Practitioners could take the identified affordances into account when designing AI‐enabled language learning applications.
Background: Dental caries is a preventable disease. This prevention covers all aspects of dentistry carried out by dentists, individuals, and society that affect the health of the oral cavity. ...Prevention services are focused on the early stages, before the onset of disease or pre-pathogenesis. At the onset stage, the disease is a primary preventive service or a service to prevent disease. This is marked by efforts to improve health (Health Promotion) and provide special protection (specific protection).Objective: To explore the differences in dental caries prevention behavior: puzzles and storytelling as a medium for health education.Methods: Quasi-experimental design research with non-equivalent control group design.Results: Prevention of dental caries in the group that was given health education by means of a puzzle game showed an average of adequate prevention behavior (20.9); with storytelling games, it shows the average of good preventive behavior (26.5); The prevention of dental caries in the control group showed an average of adequate prevention behavior (12.8), and differences in behavior between groups given puzzle games and storytelling in the prevention of dental caries in children at Pacarkembang Kindergarten Surabaya with the result ρ = 0.000.Conclusion: There is an influence between health education with puzzle games and storytelling in the prevention of dental caries in children.
Kleinian KenKen Nacin, David
The College mathematics journal,
20/9/6/, Letnik:
53, Številka:
4
Journal Article
Recenzirano
We consider the collection of all KenKen puzzles over the Klein four-group with certain symmetry conditions and classify all such puzzles by their number of solutions.
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