S Clare Stanford Beating the recession in preclinical measures of antidepression: A response to: The failure of the antidepressant drug discovery process is systemic (Hendrie CA and Pickles AR). ...Journal of Psychopharmacology, first published on December 5, 2012 as doi : 0269881112466185a . This version is no longer available. The version of record is published in Vol 27 No 5, DOI 10.1177/0269881112466185.
Background: This paper aims to create a “bridge” between research and practice by developing a practical, extensive, and clinically relevant study that translates evidence‐based findings on soft ...tissue root coverage (RC) of recession‐type defects to daily clinical practice.
Methods: This review is prepared in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) statement based on the proposed focused questions. A literature search with no restrictions regarding status or the language of publication was performed for MEDLINE and EMBASE databases up to and including June 2013. Systematic reviews (SRs), randomized clinical trials, controlled clinical trials, case series, and case reports evaluating recession areas that were treated by means of RC procedures were considered eligible for inclusion through the three parts of the study (part I, an overview of the base of SRs; part II, an alternative random‐effects meta‐analyses on mean percentage of RC and sites exhibiting complete RC; and part III, an SR of non‐randomized trials exploring other conditions not extensively evaluated by previous SRs). Data on Class I, II, III, and IV recessions, type of histologic attachment achieved with treatment, recipient‐ and donor‐site anatomic characteristics, smoking‐related outcomes, root surface conditions, tooth type and location, long‐term effectiveness outcomes, unusual conditions that may be reported during conventional daily practice, and patient‐centered outcomes were assessed as well.
Results: Of the 2,456 potentially eligible trials, 234 were included. Data on Class I, II, III, and IV gingival recessions, histologic attachment achieved after treatment, recipient‐ and donor‐site anatomic characteristics, smoking‐related outcomes, root surface conditions/biomodification, tooth type and location, long‐term effectiveness outcomes and unusual conditions that may be reported during conventional daily practice, and patient‐centered outcomes (i.e., esthetic, visual analog scale, complications, hypersensitivity, patients perceptions) were assessed. Subepithelial connective tissue (CT)‐based procedures and coronally advanced flap plus acellular dermal matrix grafts, enamel matrix derivative, or collagen matrix led to the best improvements of recession depth, clinical attachment level (CAL) gain, and keratinized tissue (KT). Some conditions, such as smoking and use of magnification, may affect RC outcomes.
Conclusions: All RC procedures can provide significant reduction in recession depth and CAL gain for Miller Class I and II recession‐type defects. Subepithelial CT graft‐based procedures provided the best outcomes for clinical practice because of their superior percentages of mean and complete RC, as well as significant increase of KT.
Periodontal plastic surgery Zucchelli, Giovanni; Mounssif, Ilham
Periodontology 2000,
June 2015, Letnik:
68, Številka:
1
Journal Article
Recenzirano
The aim of the present article is to summarize current knowledge in terms of the etiology, diagnosis, prognosis and surgical treatment of gingival recession. Whilst the main etiological factors (i.e. ...toothbrushing trauma and bacterial plaque) are well established, challenges still remain to be solved in the diagnostic, prognostic and classification processes of gingival recession, especially when the main reference parameter – the cemento–enamel junction – is no longer detectable on the affected tooth or when there is a slight loss of periodontal interdental attachment. Root coverage in single type gingival recession defects is a very predictable outcome following the use of various surgical techniques. The coronally advanced flap, with or without connective tissue grafting, is the technique of choice. The adjunctive use of connective tissue grafts improves the probability of achieving complete root coverage. Surgical coverage of multiple gingival recessions is also predictable with the coronally advanced flap and the coronally advanced flap plus the connective tissue graft, but no data are available indicating which, and how many, gingival recessions should be treated adjunctively with connective tissue grafting in order to limit patient morbidity and improve the esthetic outcome. None of the allograft materials currently available can be considered as a full substitute for the connective tissue graft, even if some recent results are encouraging. The need for future studies with patient‐based outcomes (i.e. esthetics and morbidity) as primary objectives is emphasized in this review.
This study integrates research from strategy, economics, and applied psychology to examine how organizations may leverage their human resources to enhance firm performance and competitive advantage. ...Staffing and training are key human resource management practices used to achieve firm performance through acquiring and developing human capital resources. However, little research has examined whether and why staffing and training influence firm-level financial performance (profit) growth under different environmental (economic) conditions. Using 359 firms with over 12 years of longitudinal firm-level profit data, we suggest that selective staffing and internal training directly and interactively influence firm profit growth through their effects on firm labor productivity, implying that staffing and training contribute to the generation of slack resources that help buffer and then recover from the effects of the Great Recession. Further, internal training that creates specific human capital resources is more beneficial for prerecession profitability, but staffing is more beneficial for postrecession recovery, apparently because staffing creates generic human capital resources that enable firm flexibility and adaptation. Thus, the theory and findings presented in this article have implications for the way staffing and training may be used strategically to weather economic uncertainty (recession effects). They also have important practical implications by demonstrating that firms that more effectively staff and train will outperform competitors throughout all pre- and postrecessionary periods, even after controlling for prior profitability.
Background: The purpose of this review is to evaluate the effectiveness of different root‐coverage procedures in the treatment of recession‐type defects.
Methods: The Cochrane Oral Health Group ...Trials Register, Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE were searched for entries up to October 2008. There were no restrictions regarding publication status or the language of publication. Only clinical randomized controlled trials (RCTs) with a duration ≥6 months that evaluated recession areas (Miller Class I or II ≥3 mm) that were treated by means of periodontal plastic surgery procedures were included.
Results: Twenty‐four RCTs provided data. Only one trial was considered to be at low risk of bias. The remaining trials were considered to be at high risk of bias. The results indicated a significantly greater reduction in gingival recession and gain in keratinized tissue for subepithelial connective tissue grafts (SCTGs) compared to guided tissue regeneration (GTR) with bioabsorbable membranes (GTR bms). A significantly greater gain in keratinized tissue was found for enamel matrix protein compared to a coronally advanced flap (0.40 mm) and for SCTGs compared to GTR bms plus bone substitutes. Limited data exist on the changes of esthetic conditions as related to the opinions and preferences of patients for specific procedures.
Conclusions: SCTGs, coronally advanced flaps alone or associated with other biomaterial, and GTR may be used as root‐coverage procedures for the treatment of localized recession‐type defects. In cases where root coverage and gain in keratinized tissue are expected, the use of SCTGs seems to be more adequate.
Although consumer spending typically declines in economic recessions, some observers have noted that recessions appear to increase women's spending on beauty products--the so-called lipstick effect. ...Using both historical spending data and rigorous experiments, the authors examine how and why economic recessions influence women's consumer behavior. Findings revealed that recessionary cues--whether naturally occurring or experimentally primed--decreased desire for most products (e.g., electronics, household items). However, these cues consistently increased women's desire for products that increase attractiveness to mates--the first experimental demonstration of the lipstick effect. Additional studies show that this effect is driven by women's desire to attract mates with resources and depends on the perceived mate attraction function served by these products. In addition to showing how and why economic recessions influence women's desire for beauty products, this research provides novel insights into women's mating psychology, consumer behavior, and the relationship between the two.
Wealth Disparities Before and After the Great Recession PFEFFER, FABIAN T.; DANZIGER, SHELDON; SCHOENI, ROBERT F.
The Annals of the American Academy of Political and Social Science,
11/2013, Letnik:
650, Številka:
1
Journal Article
Recenzirano
Odprti dostop
The collapse of the labor, housing, and stock markets beginning in 2007 created unprecedented challenges for American families. This study examines disparities in wealth holdings leading up to the ...Great Recession and during the first years of the recovery. All socioeconomic groups experienced declines in wealth following the recession, with higher wealth families experiencing larger absolute declines. In percentage terms, however, the declines were greater for less advantaged groups as measured by minority status, education, and prerecession income and wealth, leading to a substantial rise in wealth inequality in just a few years. Despite large changes in wealth, longitudinal analyses demonstrate little change in mobility in the ranking of particular families in the wealth distribution. Between 2007 and 2011, one-fourth of American families lost at least 75 percent of their wealth, and more than half of all families lost at least 25 percent of their wealth. Multivariate longitudinal analyses document that these large relative losses were disproportionally concentrated among lower-income, less educated, and minority households.
To what extent do personal circumstances, as compared to ideological dispositions, drive voters’ preferences on welfare policy? Addressing this question is difficult because a person's ideological ...position can be an outcome of material interest rather than an independent source of preferences. The article deals with this empirical challenge using an original panel study carried out over four years, tracking the labor market experiences and the political attitudes of a national sample of Americans before and after the eruption of the financial crisis. The analysis shows that the personal experience of economic hardship, particularly the loss of a job, had a major effect on increasing support for welfare spending. This effect was appreciably larger among Republicans than among Democrats, a result that was not simply due to a “ceiling effect.” However the large attitudinal shift was short lived, dissipating as individuals’ employment situations improved. The results indicate that the personal experience of an economic shock has a sizable, yet overall transient effect on voters’ social policy preferences.
This study investigates how the changes in labour market conditions and economic growth were associated with fertility before and during the
Great Recession
in Europe in 2002–2014. In contrast to ...previous studies, which largely concentrated at the country level, we use data for 251 European regions in 28 European Union (EU) member states prior to the withdrawal of the United Kingdom in January 2020. We apply three-level growth-curve model which allows for a great deal of flexibility in modelling temporal change while controlling for variation in economic conditions across regions and countries. Our findings show that fertility decline was strongly related to unemployment increase; this relationship was significant at different reproductive ages. Deteriorating economic conditions were associated with a stronger decline in fertility during the economic recession as compared with the pre-recession period. This evidence suggests the salience of factors such as broader perception of uncertainty that we could not capture in our models and which rose to prominence during the Great Recession. Furthermore, strongest fertility declines were observed in Southern Europe, Ireland and parts of Central and Eastern Europe, i.e. countries and regions where labour market conditions deteriorated most during the recession period. In Western Europe, and especially in the Nordic countries, fertility rates were not closely associated with the recession indicators.
Unemployment Insurance benefit durations were extended during the Great Recession, reaching 99 weeks for most recipients. The extensions were rolled back and eventually terminated by the end of 2013. ...Using matched CPS data from 2008-2014, we estimate the effect of extended benefits on unemployment exits separately during the earlier period of benefit expansion and the later period of rollback. In both periods, we find little or no effect on job-finding but a reduction in labor force exits due to benefit availability. We estimate that the rollbacks reduced the labor force participation rate by about 0.1 percentage point in early 2014.
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