•Molecular engineering based on 1,10-phenahroline ligand and related homo- and heteroleptic Ru(II) coordination complexes.•Surface functionalizations and elaboration of functionalized ...nanoparticles.•Two-photon absorption phenomena and related applications (optical power limiting and two-photon excited photodynamic therapy).
In this review, we report and discuss the specific linear and nonlinear optical properties (two-photon absorption) of original 5-substituted-1,10-phenanthroline-based Ru(II) complexes. The perspective of applications in optical power limiting (OPL) and (two-photon excited) photodynamic therapy (2PE-)-PDT, are presented together with our strategy developed in collaboration, towards the elaboration and the use of the related functionalized nano-edifices obtained by encapsulation or covalent grafting. Multifunctional nano-platforms (NPs) with potential new properties or applications are described and particularly explained by the confinement of the molecular complexes within (or at the surface of) these NPs. The stability, inertness and versatility of the involved Ru(II) complexes are more particularly highlighted in order to fit the requirements.
The precision in the design and manufacturing of scaffolds with ideal properties such as biocompatibility, biodegradability, mechanical and surface characteristics is very crucial for applications in ...tissue engineering. Furthermore, these techniques should be able to translate manufactured scaffolds from bench to potential applications. Numerous fabrication technologies have been employed to design ideal three-dimensional scaffolds with controlled nano-to-micro-structures to achieve the final biological response. This review highlights the ideal parameters (biological, mechanical and biodegradability) of scaffolds for different biomedical and tissue engineering applications. It discusses in detail about the various designing methods developed and used for the fabrication of scaffolds, namely solvent casting/particle leaching, freeze drying, thermal induced phase separation (TIPS), gas foaming (GF), powder foaming, sol-gel, electrospinning, stereolithography (SLA), fused deposition modelling (FDM), selective laser sintering (SLS), binder jetting technique, inkjet printing, laser-assisted bioprinting, direct cell writing and metal based additive manufacturing with a focus on their benefits, limitations and applicability in tissue engineering.
•We have disserted the different manufacturing methods for the scaffolds.•We have presented the various properties of ideal scaffolds for Tissue engineering.•This review highlights the merits and demerits of various scaffolds designing methods.
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•OMC was chemically and functionally modified to enhance the BTEX removal.•The pore size of OMC increased with the addition of boric acid.•The highest BTEX adsorption capacity of ...142.0 mg/g was obtained by OMC-2NC.•Chemical and functional modification enhanced the adsorption capacity by 40.5%.•The adsorption capacities followed the following (decreasing) order: X > E > T > B.
In this study, we first investigated the effects of textural parameters and surface properties of ordered mesoporous carbon (OMC) for the adsorptive removal of Benzene, Toluene, Ethylbenzene, and Xylene (BTEX) from aqueous solutions. The BET surface area, pore volume, and surface functional groups of OMC played a crucial role in affecting the adsorption performance of BTEX. Boric acid was used to increase the pore size and BET surface area of OMC from 5.94 nm to 6.74 nm and from 1276 m2/g to 1428 m2/g, respectively. Citric acid was used to introduce more oxygen-containing functional groups on the surface of OMC achieving an overall increase of 11.4% of the oxygen content. The batch adsorption experiments were conducted to evaluate the adsorption capacity for OMC and modified towards BTEX and the results showed that modified OMC exhibited a significant improvement for BTEX removal in the following order: Xylenes > Ethylbenzene > Toluene > Benzene. The BTEX adsorption capacities were improved from 8% to 15% with the addition of boric acid compared to the virgin. Surface functionalized using citric acid exhibited the total adsorption capacity of 142 mg/g with an increment of 40.5% compared to virgin OMC.
This review gives a short overview on the widespread use of nanostructured and nanocomposite materials for disease diagnostics, drug delivery, imaging and biomedical sensing applications. ...Nanoparticle interaction with a biological matrix/entity is greatly influenced by its morphology, crystal phase, surface chemistry, functionalization, physicochemical and electronic properties of the particle. Various nanoparticle synthesis routes, characterization, and functionalization methodologies to be used for biomedical applications ranging from drug delivery to molecular probing of underlying mechanisms and concepts are described with several examples (150 references).
A three-step model is adopted for the bio-conjugation of Type 1-Human Collagen (T1HC) to the chemically functionalized GaN surfaces for efficient human periodontal ligament fibroblast (HPdlF) cell ...adhesion and its utilization as a biomedical implant.
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•Bio-conjugation of Type 1-Human Collagen to the chemically functionalized GaN surfaces for efficient human periodontal ligament fibroblast cell adhesion and its utilization as a biomedical implant.•Cell survivability analysis divulges excellent cell adhesion and spreading with cell viability of over 95% after 72 h of cell culture.•Biochemically customized GaN surfaces with great soft tissue integration may be potentially used in various biomedical and dental applications.•Sequenced order of chemical and biological treatments and a systematic investigation of surface morphology and chemistry.
GaN is an aqueous and chemically stable material that has demonstrated biocompatibility with potential in biomedical engineering and offers enormous opportunities to tailor its inherent surface properties and promote efficient biomolecule adhesion with targeted functionalities. In this article, functionalization of GaN surfaces via a three-step process to enhance cell attachment and its effective utilization in in-vivo and in-vitro applications is reported. The morphology and surface chemistry of GaN surfaces were modified using sodium hydroxide and 3-aminopropyltriethoxy silane followed via bioconjugation with type 1-human collagen (T1HC), and the changes in chemical states, morphology, wettability, pH, and aqueous stability were investigated. Further, cell culture studies using human periodontal ligament fibroblast (HPdlF) cells were undertaken. The proliferation and adhesion/survivability studies at different time intervals on functionalized GaN surfaces were performed and analyzed via MTT Assay and SEM evaluation. It has been observed that the hydroxyl species and protonated amines promotes the adhesion of the silane coupling agent and human collagen, which remains stable under standard cell culture media. The chemically functionalized T1HC bio-conjugated GaN surfaces display excellent cell culture properties with complete cell adhesion and viability of ∼ 95 %. The research revealed that chemically functionalized GaN might be useful in various procedures where integrating soft tissues with implant surfaces is crucial.
Black phosphorus (BP), as a fast emerging 2D material, shows promising potential in near‐infrared (NIR) photodetection owing to its relatively small direct thickness‐dependent bandgaps. However, the ...poor NIR absorption due to the atomically thin nature strongly hinders the practical application. In this study, it is demonstrated that surface functionalization of Ag nanoclusters on 2D BP can induce an abnormal NIR absorption at ≈746 nm, leading to ≈35 (138) times enhancement in 808 (730) nm NIR photoresponse for BP‐based field‐effect transistors. First‐principles calculations reveal that localized bands are introduced into the bandgap of BP, serving as the midgap states, which create new transitions to the conduction band of BP and eventually lead to the abnormal absorption. This work provides a simple yet effective method to dramatically increase the NIR absorption of BP, which is crucial for developing high‐performance NIR optoelectronic devices.
The near‐infrared absorbance of black phosphorus is enhanced via a new strategy of silver nanoclusters functionalization. Theoretical calculations reveal that new midgap states are introduced in this process, thus activating a new optical transition route.
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