A widely-publicized, 2-year controversy at the University of Pennsylvania was recently resolved by the decision of the Board of Trustees to terminate University participation in two chemical and ...biological warfare research contracts. The controversy at Penn involved a number of broad issues, including the appropriateness of classified research on the campus, the implications of the growth of externally financed, contract research, the relevance of content in deciding on University sponsorship of research contracts, and the role of the faculty in University policy-making. Despite the Trustees' decision, these broader questions remain unresolved.
When one thinks about judicial review, one tends to envision the Supreme Court as a "countermajoritarian hero," protector of minorities from tyrannical majority rule. It is hardly surprising, then, ...that as today's top constitutional scholars debate the merits of judicial review, its defenders have returned to the notion that the Court's involvement is necessary to protect minority rights. For some, the Supreme Court's role as countermajoritarian hero is theoretically appealing, but a nagging question remains: How much does the Court actually play it? Lain examines whether the Warren Court was truly deserving of its countermajoritarian image in its criminal procedure rulings.
Tomato nutrient uptake as affected by limestone type Smith, C.B. (The Pennsylvania State University, University Park, PA); Demchak, K.T
Communications in soil science and plant analysis,
08/1990, Letnik:
21, Številka:
13/16
Journal Article
Malaria remains endemic in several countries of South America with low to moderate transmission intensity. Regional human migration through underserved endemic areas may be responsible for ...significant parasite dispersion making the disease resilient to interventions. Thus, the genetic characterization of malarial parasites is an important tool to assess how endemic areas may connect via the movement of infected individuals. Here, four sites in geographically separated areas reporting 80% of the malaria morbidity in Colombia were studied. The sites are located on an imaginary transect line of 1,500 km from the northwest to the south Pacific Coast of Colombia with a minimal distance of 500 km between populations that display noticeable ethnic, economic, epidemiological, and ecological differences.
A total of 624 Plasmodium vivax samples from the four populations were genotyped by using eight microsatellite loci. Although a strong geographic structure was expected between these populations, only moderate evidence of genetic differentiation was observed using a suite of population genetic analyses. High genetic diversity, shared alleles, and low linkage disequilibrium were also found in these P. vivax populations providing no evidence for a bottleneck or clonal expansions as expected from recent reductions in the transmission that could have been the result of scaling up interventions or environmental changes. These patterns are consistent with a disease that is not only endemic in each site but also imply that there is gene flow among these populations across 1,500 km.
The observed patterns in P. vivax are consistent with a "corridor" where connected endemic areas can sustain a high level of genetic diversity locally and can restore parasite-subdivided populations via migration of infected individuals even after local interventions achieved a substantial reduction of clinical cases. The consequences of these findings in terms of control and elimination are discussed.
This study examined the magnitude of work-related disability in postmenopausal women with breast cancer compared with healthy controls. It also examined demographic and clinical correlates of ...work-related disability in postmenopausal women with breast cancer.
This was an exploratory secondary analysis of longitudinal study.
The Work Limitations Questionnaire measured the percentage of at-work productivity loss.
The analysis revealed a significant group-by-time interaction effect (F1,40 = 4.705, P = 0.036, partial η = .105) on work-related disability. Participants with breast cancer (mean = 2.364, SE = 0.374) had significantly higher percentage of at-work productivity loss compared with the healthy control group (mean = 1.263, SE = 0.392). At baseline, cognitive-emotional symptoms were moderately to strongly associated with work-related disability. At 6 months, physical symptoms were moderately associated with work-related disability.
Women with newly diagnosed breast cancer are likely to experience higher rates of work-related disability compared with health counterparts. Health care providers should provide intervention to parallel the shift in symptoms that lead to higher work-related disability and job cessation.
About the Authors: Carolyn B. Coyne * E-mail: coynec2@pitt.edu Affiliation: Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America ...Citation: Coyne CB (2018) Horsepox: Framing a dual use research of concern debate. The four author groups represented in these Opinions include Drs. Ryan S. Noyce and David H. Evans, two authors of a recent PLOS ONE study on Horsepox virus 1, Dr. Volker Thiel, who served as Academic Editor for the article describing the study, and Dr. Thomas Inglesby, Jr. and Dr. Kevin M. Esvelt, both of whom have advocated for changes in the peer reviewing and publishing of DURC-related research. The publishing of this study led to intense debate among the public and scientific community as to whether this type of study should be permissible given that the methods described could be used to synthesize any poxvirus, particularly variola virus, which was declared eradicated in 1980 and is the infectious agent responsible for smallpox.
ECONOMIC OUTLOOK 2016; QA ANAND SANWAL Flamm, Matthew
Crain's New York Business,
12/2015, Letnik:
31, Številka:
50
Journal Article, Trade Publication Article
TECHNOLOGY ANAND SANWAL WHO HE IS Chief executive and co-founder, CB Insights AGE 41 BORN Whitehouse Station, N.J. EDUCATION University of Pennsylvania, the Wharton School BONA FIDES In 2008, with ...colleague Jonathan Sherry, launched CB Insights, a venture-capital database and research company focused on startups; it is now a go-to resource for investors, bankers, analysts, reporters, budding tech companies and anyone else who wants to get a handle on the stars of the new economy.
Ihuoma O Njoku,1 Eliza L Chin,2 Meredith CB Adams3 1Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA; 2American Medical Women's ...Association, Schaumburg, IL, USA; 3Departments of Anesthesiology, Artificial Intelligence, Translational Neuroscience, and Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USACorrespondence: Ihuoma O Njoku, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA, Email Drihuomanjoku@gmail.com
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