-
High reactive oxygen species levels are detected at the end of the chronological life span of translocant yeast cellsSims, Jason ...Chromosome translocation is a major genomic event for a cell, affecting almost every of its life aspects ranging from metabolism, organelle maintenance and homeostasis to gene maintenance and ... expression. By using the bridge-induced translocation system, we defined the effects of induced chromosome translocation on the chronological life span (CLS) of yeast with particular interest to the oxidative stress condition. The results demonstrate that every translocant strain has a different CLS, but all have a high increase in reactive oxygen species and in lipid peroxides levels at the end of the life span. This could be due to the very unique and strong deregulation of the oxidative stress network. Furthermore, the loss of the translocated chromosome occurs at the end of the life span and is locus dependent. Additionally, the RDH54 gene may play a role in the correct segregation of the translocant chromosome, since in its absence there is an increase in loss of the bridge-induced translocated chromosome.Vir: Molecular genetics and genomics : MGG. - ISSN 1617-4615 (Vol. 291, iss. 1, Febr. 2016, str. 423-435)Vrsta gradiva - članek, sestavni delLeto - 2016Jezik - angleškiCOBISS.SI-ID - 1538198212
Avtor
Sims, Jason |
Bruschi, Carlo V. |
Bertin, Chloé |
West, Nicole |
Breitenbach, Michael |
Schroeder, Sabrina |
Eisenberg, Tobias |
Rinnerthaler, Mark |
Raspor, Peter |
Tosato, Valentina
Teme
ageing |
chromosomal translocation |
lifespan |
yeast |
oxidative stress |
staranje |
kromosomske translokacije |
kvasovke |
oksidativni stres
![loading ... loading ...](themes/default/img/ajax-loading.gif)
vir: Molecular genetics and genomics : MGG. - ISSN 1617-4615 (Vol. 291, iss. 1, Febr. 2016, str. 423-435)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Sims, Jason | ![]() |
Bruschi, Carlo V. | ![]() |
Bertin, Chloé | ![]() |
West, Nicole | ![]() |
Breitenbach, Michael | ![]() |
Schroeder, Sabrina | ![]() |
Eisenberg, Tobias | ![]() |
Rinnerthaler, Mark | ![]() |
Raspor, Peter | 04001 |
Tosato, Valentina | ![]() |
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Obvestilo
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Mesto prevzema | Status gradiva | Rezervacija |
---|
Prosimo, počakajte trenutek.