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Zavod za zdravstveno varstvo, Celje (ZZVCE)
  • Epidemiologija invazivnih okužb s haemophilusom influenzae tip B pri otrocih v Sloveniji, 1993-1995 = Epidemiology of invasive Haemophilus influenzae type B disease in children in Slovenia, 1993-1995
    Čižman, Milan ...
    Background. Haemophilus influenzae type b is frequent cause of systemic infections in children under 5 years of age. Active immunization against Haemophilus influenzae is rountinely performed in many ... countries. A basic knowledge of epidemiology of these infections in Slovenia is necessary before introduction of vaccination. Patients and methods. Children aged 0 to 14 yearswith Haemophilus influenzae type b isolated from blood, CSF or other normally sterile body site in a period from January 1993 to December 1995 wereincluded in a nationwide prospective study. Results. In a 3-year period, 56 invasive Hib infections were observed, representing 96.6% of all Haemophilus influenzae isolates. Meningitis was the most frequent clinical syndrome (68%), followed by pneumonia (12%), bacteremia/sepsis (7%) and other focal infections. The incidence of Hib disease in children under 5 years of age was 16.4/100,000, the incidence of Hib meningitis was 13.35/100,000 per year in the same age group. Mortality was 3.6%. Conclusions. Compared to developed countries a lower incidence of invasive Hib disease was observed in our 3-year study. The results obtained will provide a basis for an cost-benefit evaluation of potential benefits of Hib vaccination in Slovenia.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Let. 66, št. 9, 1997, str. 469-472)
    Vrsta gradiva - članek, sestavni del
    Leto - 1997
    Jezik - slovenski
    COBISS.SI-ID - 6926809

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