The recording of the maxillo-mandibular relationship (MMR) is an essential and unavoidable step that occurs at different stages of treatment during a prosthetic rehabilitation. Tissue duality is a major problem in metal partial dentures (MPD), especially in complete and large edentulisms, and is responsible for occlusal inaccuracies resulting in restorations that are not integrated with the patient’s manducatory system. In order to perform this step, the practitioner must choose the right material, make the appropriate support, and adopt a reliable and reproducible technique that is adapted to the clinical situation and the prosthetic step. The objective of this work is to suggest a simple and codified approach, which guarantees a reliable recording of the maxillo-mandibular relationship, adapted to the particularities of the supporting structures and taking into consideration the clinical sequence for an optimal occlusal-functional integration of the future metallic partial denture.