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  • Xiang, Yonggang; Fu, Chen; Breiding, Tom; Sasmal, Pijus K; Liu, Haidong; Shen, Qi; Harms, Klaus; Zhang, Lilu; Meggers, Eric

    Chemical communications (Cambridge, England), 01/2012, Letnik: 48, Številka: 57
    Journal Article

    We here introduce octahedral silicon serving as a structural center for the design of hydrolytically stable bioactive complexes as demonstrated with the generation of silicon-based high affinity DNA binders. This proof-of-principle study suggests that octahedral silicon complexes are falsely neglected, promising structural templates for widespread applications in chemical biology and medicinal chemistry.