High-quality seismic data are the basis for stratigraphic imaging and interpretation, but the existence of random noise can greatly affect the quality of seismic data. At present, most understanding and processing of random noise still stay at the level of Gaussian white noise. With the reduction of resource, the acquired seismic data have lower signal-to-noise ratio and more complex noise natures. In particular, the random noise in the desert area has the characteristics of low frequency, non-Gaussian, nonstationary, high energy, and serious aliasing between effective signal and random noise in the frequency domain, which has brought great difficulties to the recovery of seismic events by conventional denoising methods. To solve this problem, an improved feed-forward denoising convolution neural network (DnCNN) is proposed to suppress random noise in desert seismic data. DnCNN has the characteristics of automatic feature extraction and blind denoising. According to the characteristics of desert noise, we modify the original DnCNN from the aspects of patch size, convolution kernel size, network depth, and training set to make it suitable for low-frequency and non-Gaussian desert noise suppression. Both simulation and practical experiments prove that the improved DnCNN has obvious advantages in terms of desert noise and surface wave suppression as well as effective signal amplitude preservation. In addition, the improved DnCNN, in contrast to existing methods, has considerable potential to benefit from large data sets. Therefore, we believe that it can open a new direction in the area of seismic data processing.