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  • Htr2c Splice Variants and 5...
    Isles, Anthony R

    Trends in endocrinology and metabolism, 08/2017, Letnik: 28, Številka: 8
    Journal Article

    Serotonin 2C receptor (5HT R) exists as different isoforms as a result of alternate splicing. A truncated variant (5HT R-trunc) has no canonical receptor function and yet shows robust expression levels throughout the brain. Recent work has demonstrated the biochemical role of this isoform and how altering levels of 5HT R-trunc leads to changes in behaviour.