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  • Assessment of dopamine rece...
    Wagner, Jr, H N; Burns, H D; Dannals, R F; Wong, D F; Langström, B; Duelfer, T; Frost, J J; Ravert, H T; Links, J M; Rosenbloom, S B

    Annals of neurology, 1984, Letnik: 15 Suppl
    Journal Article

    We describe the use of carbon-11-labeled 3-N-methylspiperone, a ligand that preferentially binds to dopamine receptors in vivo, to image the receptors by positron emission tomography scanning in baboons and, for the first time, in a human. The method has now been used in 58 humans for noninvasive assessment of the state of brain dopamine receptors under normal and pathological conditions.