The impact resistant behaviors of boride reinforced Ti-6Al-4 V functionally graded materials prepared by spark plasma sintering (SPS) with compositional gradients of 90°, 84°, 82°and 79° were investigated based on the experimental test and the finite element method. The material constitutive parameters of the boride reinforced Ti-6Al-4 V alloys with different TiB2 contents were determined, and the Johnson Holmquist Ceramics (JH-2) model and a cohesive contact model were established and developed to predict the crack propagation and the impact resistance behaviors of the materials. The calculated results agreed well with the split Hopkinson press bar (SHPB) experimental results. The optimum material composition gradient design scheme with a continuous transition property from a high-toughness end to a high-strength end along the thin-thickness direction was determined. The G84 (0, 0, 15, 30 wt% TiB2) had the best impact resistance, with Young's modulus of 55505±5 GPa, compressive strength of 2045±5 MPa, and microhardness ranging from 535±5HV to 1246±5HV, exhibiting high strength and hardness at a high-strength end that can prolong the interaction time between the impactor and the materials, while the elongation of 39 % at its high-toughness end can cause tensile deformation, consuming impact kinetic energy efficiently. Combined with the experimental and numerical analysis results, the impact resistance and the crack-alleviated mechanisms of boride reinforced Ti-6Al-4 V functionally graded materials were discussed. Reducing the compositional gradient can alleviate the difference in coefficients of thermal expansion between composites, which may lead to strengthen the reflected wave, lower the compression wave, and suppress high-strength end failure efficiently, meaning of relieving the stress concentration under extreme service conditions. Moreover, the effects of the presence of the borides, such as in situ-formed TiB, remained TiB2at al., the dislocation defects and the whisker-like TiB on the armour materials resist fracture and layer cracking were also analyzed. This work provided a method for designing high performance of boride reinforced Ti-6Al-4 V functionally graded materials with high impact resistance and thin thickness. •The boride reinforced Ti-6Al-4 V functionally graded materials exhibiting great promise in good impact resistance were designed and prepared.•The material constitutive parameters of the boride reinforced Ti-6Al-4 V alloys, the Johnson Holmquist Ceramics (JH-2) model and a cohesive contact model were established to predict the impact resistance behaviors of the materials.•The impact resistance and the crack-alleviated mechanisms of boride reinforced Ti-6Al-4 V functionally graded materials were discussed.•This work provided a method for designing high performance of boride reinforced Ti-6Al-4 V functionally graded materials with high impact resistance and thin thickness.