Individuals with autism spectrum disorder (ASD) characteristically demonstrate interest in a restricted range of activities. Embedding interests into the learning environment is a strategy used to establish motivation and promote participation in alternative activities. This review includes an evaluation of the quality of single-case and group-based research on embedding interests for individuals with ASD. Twenty studies with 79 participants were appraised according to two quality rubrics. Evidence was analyzed overall and within categories of dependent variables. Primary outcomes included social/communication skills and task-engagement/accuracy/productivity. Results show insufficient support for use of this intervention according to one rubric and mixed but sufficient support overall according to an alternative rubric. Most research support targets social or communication skills. Implications for practice are identified.