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  • Comparative genomics of hum...
    Šantak, Maja; Mlinarić-Galinović, Gordana; Vilibić-Čavlek, Tatjana; Tabain, Irena

    Archives of virology, 11/2018, Letnik: 163, Številka: 11
    Journal Article

    Although human rubulavirus 2 (HPIV2) is an important respiratory pathogen, little is known about its molecular epidemiology. We performed a comparative analysis of the full-length genomes of fourteen HPIV2 isolates belonging to different genotypes. Additionally, evolutionary analyses (phylogenetic reconstruction, sequence identity, detection of recombination and adaptive evolution) were conducted. Our study presents a systematic comparative genetic analysis that complements prior analyses and utilizes full-length HPIV2 genomes to provide a basis for future work on the clinical significance, molecular variation and conservation, and evolution of HPIV2.