Non-specific low back pain (NSLBP) is a common musculoskeletal condition causing functional disability and affecting the quality of life. Exercise therapy especially Dynamic Stabilisation Exercises (DSE) and Muscle Energy Techniques (MET) are frequently used in the treatment of NSLBP. However there are some inconsistencies with the use of DSE and the physiological mechanisms underlying the therapeutic effects of MET are currently unclear, and a review of literature on these interventions recommend further research. Therefore this study was designed to determine the effect of DSE and MET for the management of patients with NSLBP. This study will involve 141 participants with chronic NSLBP. They will be randomised into three groups: two intervention groups i.e. DSE plus MET group, DSE alone and control (standard physiotherapy treatment). Outcomes that include trunk range of motion, Transverse Abdominus contraction rate, trunk muscles endurance, level of pain perception, quality of life, functional disability, activity limitation and participation restrictions will be assessed at baseline, 6th and 12th week of intervention, however, while follow-up assessment at 3-months after the intervention. Data will be analysed using descriptive statistics and inferential statistics of repeated ANOVA; P < 0.05. The study outcome will determine the combined effect of DSE plus MET on trunk muscles functions, level of pain perception, quality of life, functional disability, activity limitations and participation restrictions in patients with chronic NSLBP. www.ClinicalTrials.gov : NCT03449810