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Parker, Gemma L.; Smith, Laura K.; Baxendale, Ian R.
Tetrahedron, 03/2016, Letnik: 72, Številka: 13Journal Article
The advances made in chemistry during the last 70 years are excellently illustrated by the development of the industrial synthesis of vitamin A, a diterpene crucial in preventing premature death and visual problems. Arens and van Dorp published the first route in 1946, and critical contributions have been made by a number of scientists since, benefitting from fruitful collaborations between industry and academia. However, these improvements have been mostly incremental, and the work has been performed by a limited number of companies; as yet, there is still no ‘ideal’ synthesis of vitamin A. Display omitted
