The study is carried out to investigate the haemogram of yellow-bellied house gecko in Odisha, India. Fifteen adult lizards of each sex were collected from the coastal area of Rajnagar block of Kendrapara, 754 225, Odisha, located in 20° 20′ N to 20° 37′ N latitude and 86° 14′ E to 87° 01′ E longitude. One millilitre of blood was collected from the ventral tail vein and transferred into vials containing ethylenediaminetetraacetic acid (EDTA) and then transported in icebox to laboratory. The morphology of blood cells along with haematological parameters like haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), total leucocyte count (TLC), total platelet count (TPC), and differential leucocyte count (DLC) was calculated using standard procedures. Statistical analyses like correlation and t test were done. The study revealed that the TLC shows significant difference ( t 0.01 ) while the percentage of eosinophils is found to be significant at t 0.05 between both sexes of lizard. The mean values of all other parameters are also showing difference between males and females of Hemidactylus flaviviridis Ruppell, 1835. The correlation with R 2 values varies in males and females with respect to the parameters analysed. Some parameters are positively correlated with each other, and others are found to be negatively correlated. The data obtained could be useful in knowing the difference of haematological parameters between sexes of Hemidactylus flaviviridis .