This work focuses on high-cycle fatigue and quasi-static tensile performance of additively manufactured and wrought 17–4 stainless steel. Test specimens were manufactured using a Markforged Metal X printer via the atomic diffusion additive manufacturing process or machined from commercial stock. High-cycle fatigue testing showed that wrought specimens could sustain higher loads at 10 6 cycles (565 MPa) as compared to additively manufactured specimens with solid infill (216 MPa) and triangular infill (136 MPa). The mass-normalized fatigue responses of the additively manufactured specimens were similar when comparing in-fill type while wrought specimens performed roughly 50% better across the range from 10 4 to 3.5 × 10 7 cycles.