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  • Drug resistance in inflamma...
    Moreau, Jacques; Mas, Emmanuel

    Current opinion in pharmacology, 12/2015, Letnik: 25
    Journal Article

    Highlights • Treatment goal evolves from clinical remission to mucosal healing or deep remission. • Thiopurines are poorly effective in adults and had severe adverse events. • Anti-TNFα should be rapidly used in severe patients. • Drug development is mandatory, addressing new targets.