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Recenzirano
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Aygören-Pürsün, Emel, MD; Magerl, Markus, MD; Graff, Jochen, MD; Martinez-Saguer, Inmaculada, MD; Kreuz, Wolfhart, MD; Longhurst, Hilary, MD, PhD; Nasr, Iman, MD; Bas, Murat, MD; Straßen, Ulrich, MD; Fang, Lei, PhD; Cornpropst, Melanie, PhD; Dobo, Sylvia, MD; Collis, Phil, PhD; Sheridan, William P., MD; Maurer, Marcus, MD, PhD
Journal of allergy and clinical immunology, 09/2016, Letnik: 138, Številka: 3Journal Article
For several decades, attenuated androgens were the only oral prophylaxis drugs widely used in HAE despite their androgenic and anabolic effects.8 Managing HAE with safe oral medicines is considered a critical unmet need.9 Given the encouraging results of this trial, studies of longer duration are indicated to understand the durability of benefit and long-term tolerability and safety profile of oral avoralstat.
