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  • Photoregulated release of c...
    Agasti, Sarit S; Chompoosor, Apiwat; You, Chang-Cheng; Ghosh, Partha; Kim, Chae Kyu; Rotello, Vincent M

    Journal of the American Chemical Society, 04/2009, Letnik: 131, Številka: 16
    Journal Article

    An anticancer drug (5-fluorouracil) was conjugated to the surface of gold nanoparticles through a photocleavable o-nitrobenzyl linkage. In this system, the particle serves as both cage and carrier for the therapeutic, providing a nontoxic conjugate that effectively releases the payload upon long wavelength UV irradiation.