碩士 國立臺北科技大學 化學工程研究所 97 Ultra-high molecular weight polyethylene (UHMWPE) sliding against CoCrMo ally is common in total joint implant. These polyethylene wear particles lead to osteolysis and that result in loosening and thus failure of the implant. Periprosthetic fluid presents between artificial joint surfaces and acts as a lubricant which prevents wear and reduces friction. Therefore, the constituent of synovial fluid play different roles in the joint lubrication and biomolecular interaction effect the tribological performance of artificial joint. In the present study, we have to further investigate the influence of lubricant composition on the tribological performance of artificial joints, in order to identify the roles of these lubricants in the synovial fluid. In the study, we mix albumin,globulin,hyaluronic acid and lipid in terms of its physiological concentration for simulated synovial fluid and then add different concentration of composition to simulated synovial fluid. To study concentration of com