E-viri
Recenzirano
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Antipova, Alena A; Sokolsky, Tanya D; Clouser, Christopher R; Dimalanta, Eileen T; Hendrickson, Cynthia L; Kosnopo, Cisilya; Lee, Clarence C; Ranade, Swati S; Zhang, Lei; Blanchard, Alan P; McKernan, Kevin J
Journal of biomolecular techniques, 12/2009, Letnik: 20, Številka: 5Journal Article
Identifying genetic variants and mutations that underlie human diseases requires development of robust, cost-effective tools for routine resequencing of regions of interest in the human genome. Here, we demonstrate that coupling Applied Biosystems SOLiD system-sequencing platform with microarray capture of targeted regions provides an efficient and robust method for high-coverage resequencing and polymorphism discovery in human protein-coding exons.
