The skin, an organ with high accessibility, represents the site of significant changes, with high social and psychological impact on the patient's quality of life, by its evolution poten-tial, but mainly by its aesthetic prejudice generated by the persistent/permanent lesions. The most eligible criteria of classifying hyperpigmentation are etiological: genetic associat-ed with endocrinological pathologies, metabolic diseases, post-inflammatory or infections diseases, but also with physical/chemical agents, tumor and idiopathic pathology. Regard-less of the etiological agents involved, all hypermelanoses are the consequence of melanic pigment excess, histologically localized in the dermis/epidermis, most often manifested secondary to quantitative disorders (increase in melanin production) and occasionally to qualitative disorders (increase in melanocytes activity). Often asymptomatic and chronic, cutaneous hyperpigmentation represents a real issue for the patients, because of its emo-tional and psychological consequences.