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Ichiishi, Naoko; Brooks, Allen F; Topczewski, Joseph J; Rodnick, Melissa E; Sanford, Melanie S; Scott, Peter J. H
Organic letters, 06/2014, Letnik: 16, Številka: 12Journal Article
A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)(aryl)iodonium salts is described. This protocol utilizes 18FKF to access 18F-labeled electron-rich, -neutral, and -deficient aryl fluorides under a single set of mild conditions. This methodology is applied to the synthesis of protected versions of two important radiotracers: 4-18Ffluorophenylalanine and 6-18FfluoroDOPA.
![Copper-Catalyzed [18F]Fluor...](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/1523-7060/medium "Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodonium Salts")
