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  • Inside Back Cover: Rational...
    Embaby, Ahmed M.; Schoffelen, Sanne; Kofoed, Christian; Meldal, Morten; Diness, Frederik

    Angewandte Chemie International Edition, July 2, 2018, 2018-07-02, Letnik: 57, Številka: 27
    Journal Article

    Site‐selective cysteine arylation has been achieved by rational 2D reactivity tuning of fluorobenzene probes. In their Communication on page 8022 ff., M. Meldal, F. Diness et al. demonstrate how probes may be tailored to selectively target cysteine‐containing proteins by adjusting the numbers of fluoro substituents (Fx) and by selecting substituents based on their electron‐withdrawing capacity represented by their Hammett σp constant.