The floristic investigation of the Ionian island of Kalamos resulted in the addition of 275 specific and infraspecific taxa, which are reported here, to a present total of 502 taxa. For each newly recorded taxon local distribution and habitat types are presented. Convolvulus pentapetaloides and Malcolmia graeca subsp. hydraea are reported for the first time from the Ionian islands. Some of the new records concern rare taxa in Greece or regional endemics, which are, therefore, chorologically significant, such as Alkanna corcyrensis, Stachys ionica, Heptaptera colladonioides. A brief description of some of the vegetation types of the island is given. The results of floristic analysis and phytogeographical aspects demonstrate the pronounced Mediterranean character of the island’s flora. Na otoku Kalamos smo s floristično raziskavo odkrili 275 novih taksonov na nivoju vrste in nižje ob do sedaj že poznanih 502 taksonih. Za vsak novo odkrit takson predstavljamo lokalno razširjenost in habitatni tip. Taksona Convolvulus pentapetaloides in Malcolmia graeca subsp. hydraea smo na ionskih otokih našli prvič. Nekatere nove najdbe so redki taksoni ali lokalni endemiti, kot so Alkanna corcyrensis, Stachys ionica, Heptaptera colladonioides in so horološko pomembni. Podali smo tudi kratek opis nekaterih vegetacijskih tipov otoka. Rezultati floristične analize in fitogeografskih vidikov kažejo izrazito mediteranski značaj preučevanega rastlinstva.