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Gastl, Günther; Spizzo, Gilbert; Obrist, Peter; Dünser, Martina; Mikuz, Gregor
The Lancet (British edition), 12/2000, Letnik: 356, Številka: 9246Journal Article
The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immuno-histochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35·6% of samples and was associated with poor disease-free and overall survival.
