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  • Influence of surface modifi...
    Yoshinari, M; Oda, Y; Kato, T; Okuda, K

    Biomaterials, 07/2001, Letnik: 22, Številka: 14
    Journal Article

    The antibacterial effect of surface modifications to titanium on Porphyromonas gingivalis ATCC 33277 and Actinobacillus actinomycetemcomitans ATCC 43718 was evaluated. Surface modifications were performed with dry processes including ion implantation (Ca +, N +, F +), oxidation (anode oxidation, titania spraying), ion plating (TiN, alumina), and ion beam mixing (Ag, Sn, Zn, Pt) with Ar + on polished pure titanium plates. F +-implanted specimens significantly inhibited the growth of both P. gingivalis and A. actinomycetemcomitans than the polished titanium. The other surface-modified specimens did not exhibit effective antibacterial activity against both bacteria. No release of the fluorine ion was detected from F-implanted specimens under dissolution testing. This result and the characterization of the F +-implanted surfaces suggested that the possible antibacterial mechanism of the F +-implanted specimen was caused by the formation of a metal fluoride complex on the surfaces. In addition, F +-implanted surfaces did not inhibit the proliferation of fibroblast L929-cells. These findings indicate that surface modification by means of a dry process is useful in providing antibacterial activity of oral bacteria to titanium implants exposed to the oral cavity.