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Li, Hao; Luan, Zheng-Jiao; Zheng, Gao-Wei; Xu, Jian-He
Advanced synthesis & catalysis, May 26, 2015, Letnik: 357, Številka: 8Journal Article
An enzymatic process for the efficient asymmetric reduction of 3H‐indoles as well as 3H‐indole iodides was developed for the first time. Using a new imine reductase identified from Paenibacillus lactis (PlSIR), various chiral indolines were facilely synthesized in good yields and excellent enantiopurities (up to >99% ee) under mild reaction conditions.
